Abstract:ABSTRACT:Rationale: Previous studies have suggested that antihistamines may be therapeutic in some patients with asthma. Variation in genes along the histamine production, response, and degradation pathway may be important in predicting response to antihistamines. We hypothesize that genetic variation in genes of the histamine pathway differs between children with allergic versus non-allergic asthma.Methods: Children 7-18 years of age (n=118) with asthma participated in this IRB-approved protocol and were clas… Show more
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