Genetic variability of the murine creatine kinase B gene locus and related pseudogenes in different inbred strains of mice

Deursen, Jan van; Schepens, Jan; Peters, W.H.M.; Meijer, Dies; Grosveld, Gerard; Hendriks, Wiljan; Wieringa, Bé

doi:10.1016/0888-7543(92)90383-4

Cited by 23 publications

(10 citation statements)

References 33 publications

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“…An indication of the re latedness of the clones was that their 3' untranslated re gions, which usually show the highest amount of polymor phism in cDNA [19,20], were identical. The degree of sequence variation described here is not usually found in DNA coding other eukaryotic proteins regions [21] and Kreitman [22] has for example reported that 11 different isolates of Drosophila melanogaster had only one amino acid change in their alcohol dehydrogenase genes.…”

Section: Discussionmentioning

confidence: 99%

Sequence Polymorphisms of cDNA Clones Encoding the Mite Allergen Der p I

Chua¹,

Kehal²,

Thomas³

1993

Int Arch Allergy Immunol

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Sequence information has been obtained from 5 cDNA clones encoding the major house dust mite allergen Der p I, including one which codes for the full length preproenzyme form of the molecule. All translated sequences were unique with 1–3 differences between each clone. 4/5 of the substitutions found were to residues found in Der f l and two positions had a substitution in more than one clone. The polymorphisms included residues already described to be in T cell epitopes, so as well as being necessary to consider them in the construction of synthetic allergens, the substitutions will be important for the interpretation of experimental and genetic studies.

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Section: Discussionmentioning

confidence: 99%

Sequence Polymorphisms of cDNA Clones Encoding the Mite Allergen Der p I

Chua¹,

Kehal²,

Thomas³

1993

Int Arch Allergy Immunol

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“…X53859; Garber et al, 1990), and a 70% match with the mouse, Mus musculus, CK gene (GenBank Accession No. M74149; van Deursen et al, 1992). Using these alignments we determined the linear arrangement of the belonid exon/intron positions for the approximately 1000 bp CK fragment amplified by the CK1 and CK2 primers.…”

Section: Molecular Characterizationmentioning

confidence: 99%

Molecular phylogenetics and biogeography of transisthmian and amphi-Atlantic needlefishes (Belonidae: Strongylura and Tylosurus): perspectives on New World marine speciation

Banford¹,

Bermingham²,

Collette³

2004

Molecular Phylogenetics and Evolution

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“…A specific antisense oligonucleotide probe complementary to nucleotides 3787-3837 of the coding sequence of murine CKB gene [26] was radioactively labeled, purified, hybridized, and detected as before [27].…”

Section: In Situ Hybridizationmentioning

confidence: 99%

Identification of new regional marker proteins to map mouse brain by 2‐D difference gel electrophoresis screening

et al. 2008

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To screen for new region-specific protein markers we compared the proteome maps of the primary visual and somatosensory areas V1 and S1 in mouse brain using 2-D difference gel electrophoresis (2-D DIGE). Twenty-three protein spots showed a statistically significant difference in expression level between V1 and S1, with 52% appearing more abundantly in V1. Twenty-six proteins were mass spectrometrically identified in 22 spots. To assess the validity of this list of potential areal markers generated by 2-D DIGE, the effective area-specific distribution profile of creatine kinase brain subtype (CKB), a protein with a clearly higher expression level in S1, was monitored with in situ hybridization. The mRNA expression profile of CKB displayed a clear area-specific distribution, which allowed demarcation of S1 and its topographical borders with neighboring neocortical areas. This proteomic study demonstrates the innovative application of 2-D DIGE and MS to select new regional markers for neuroscience research.

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Genetic variability of the murine creatine kinase B gene locus and related pseudogenes in different inbred strains of mice

Cited by 23 publications

References 33 publications

Sequence Polymorphisms of cDNA Clones Encoding the Mite Allergen <i>Der </i><i>p</i> I

Sequence Polymorphisms of cDNA Clones Encoding the Mite Allergen <i>Der </i><i>p</i> I

Molecular phylogenetics and biogeography of transisthmian and amphi-Atlantic needlefishes (Belonidae: Strongylura and Tylosurus): perspectives on New World marine speciation

Identification of new regional marker proteins to map mouse brain by 2‐D difference gel electrophoresis screening

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