Genetic Variability of Permanent Tooth Crowns as Ascertained from Twin Data

Mizoguchi, Yuji

doi:10.1537/ase1911.85.301

Cited by 26 publications

(25 citation statements)

References 11 publications

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“…Most earlier studies applied heritability estimation procedures to univariate data. The estimates incorporated a number of inseparable genetic and environmental variance components, and/or assumed no genetic interaction (epistasis) or genotype-environment interaction (Bulmer, 1970;Smith, 1974;Mizoguchi, 1977).…”

Section: Multivariate Analysesmentioning

confidence: 99%

“…In fact, most evidence points to mesiodistal and buccolingual crown dimensions being to the largest extent genetically determined (e.g., Alvesalo and Tigerstedt, 1974;Gam, 1977). Although morphogenetic field theory (Butler, 1939;Dahlberg, 1945) implies that there should be distinct patterns of heritability within each tooth class (incisor, premolar, and molar), results of previous investigations in twins and Siblings have been inconsistent (e.g., Lundstrom, 1948;Alvesalo and Tigerstedt, 1974;Mizoguchi, 1977).…”

Section: Introductionmentioning

confidence: 99%

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Genetic Covariance Structure of Incisor Crown Size in Twins

et al. 1995

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Abstract. Previous studies of tooth size in twins and their families have suggested a high degree of genetic control, although there have been difficulties separating the various genetic and environmental effects. A genetic analysis of variation in crown size of the permanent incisors of South Australian twins was carried out, with structural equation modeling used to determine the relative contributions of genetic and environmental factors. Maximum mesiodistal crown dimensions of maxillary and mandibular permanent incisors were recorded from dental models of 298 pairs of twins, including 149 monozygous (MZ) and 149 dizygous (DZ) pairs. The analysis revealed that: (i) an adequate fit required additive genetic and unique environmental components; (ii) augmenting the model with non-additive genetic variation did not lead to a Significant improvement in fit; (iii) there was evidence of shared environmental influences in the upper central incisors of males; (iv) the additive genetic component constituted a general factor loading on all eight teeth, with group factors loading on antimeric pairs of teeth; (v) unique environmental effects were mostly variable-specific; (vi) most factor loadings on antimeric tooth pairs could be constrained to be equal, indicating a symmetry of genetic and environmental influences between left and right sides; and (vii) estimated heritability of the incisor mesiodistal dimensions varied from 0.81 to 0.91.

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Section: Multivariate Analysesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Genetic Covariance Structure of Incisor Crown Size in Twins

et al. 1995

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“…Both the tooth size proportion and nonmetric dental traits are thought to be formed strongly under genetic control and developed in the young childhood, which are more conservative against environmental factors than the bone tissue (e.g. Bowden and Goose, 1969;Mizoguchi, 1977;Townsend and Brown, 1978;Hanihara and Ueda, 1979;Hanihara and Hanihara, 1989). The differences in these dental characteristics are not particularly suggestive of genetic consistency between the Phum Snay and surrounding modern populations.…”

Section: Discussionmentioning

confidence: 99%

On the origin of pre-Angkorian peoples: perspectives from cranial and dental affinity of the human remains from Iron Age Phum Snay, Cambodia

Matsumura

Domett

O’Reilly

2011

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This article presents the results of an assessment of the morphological affinities of the skeletal remains from a large mortuary assemblage, dated to Iron Age, in Phum Snay, a village in Banteay Meanchey Province, northwest Cambodia. The purpose of the research is to address the origin of these pre-Angkorian people. Multivariate comparisons using cranial and dental metrics, as well as dental nonmetric traits, demonstrate that the characteristic affinities intermediate between the early Holocene Hoabinhian groups akin to Australo-Melanesians and the present-day people in the mainland Southeast Asia. This finding suggests that the ancient people of Phum Snay preserved genetic traits of early indigenous populations, whereas modern mainland Southeast Asians, including Cambodians, were more affected by gene flow from later migrants from East Asia into this region.

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“…However, this is not necessarily inconsistent with the present results where UI2 were both environmentally and phenotypically more variable than UI1. Mizoguchi (1977), using 191 monozygotic and 75 like-sexed dizygotic twin pairs of Japanese, estimated heritabilities corrected for common environmental factors within twin pairs for the MD crown diameters of permanent teeth. The respective estimates in males and females for the incisors were as follows: 1.23 and 0.99 for UI1; 1.11 and 0.87 for UI2; 1.09 and 0.66 for LI1; and 1.08 and 0.49 for LI2.…”

Section: Differences In Cvs Between Central and Lateral Incisorsmentioning

confidence: 99%