Genetic testing in other GI diseases

The Incidence and Gastrointestinal Infectious Risk of Functional Gastrointestinal Disorders in a Healthy US Adult Population

“…As a group of conditions, functional disorders were estimated to account for more than 11 million ambulatory care visits in 2004, roughly equating to four visits per every 100 persons in the United States ( 2 ), making them one of the most costly and burdensome group of gastrointestinal disorders with considerable societal impact. Although the pathoetiology of these disorders is poorly understood and likely multifactorial, several general mechanisms including gutbrain axis dysfunction, mucosal barrier disruption, gastrointestinal dysmotility, microbiota disturbances, infl ammation, visceral hypersensitivity, diet, and genetic predisposition have been implicated in the generation of symptoms associated with these disorders ( 3,4 ). Functional gastrointestinal disorders (FGDs) are recognized sequelae of infectious gastroenteritis (IGE).…”