Genetic Testing, an Optimal Strategy for Lynch Syndrome Identification

Hudler, Petra

doi:10.1007/978-94-007-6597-9_4

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DNA Alterations in Lynch Syndrome 2013

DOI: 10.1007/978-94-007-6597-9_4

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Genetic Testing, an Optimal Strategy for Lynch Syndrome Identification

Petra Hudler

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2015

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Contemporary proteomic strategies for clinical epigenetic research and potential impact for the clinic

Hudler¹,

Paska

Komel³

2015

Expert Review of Proteomics

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Novel proteomic methods are revealing the intricacy of the epigenetic landscape affecting gene regulation and improving our knowledge of the pathogenesis of complex diseases. Despite the enormous amount of data regarding epigenetic modifications present in DNA and histones, deciphering their biological relevance in the context of the disease and health is currently still an ongoing process. Here, we consider the relationship between epigenetic research in tumorigenesis and the prospect of knowledge transfer to clinical use, focusing primarily on the epigenetic histone post-translational modifications, which could be used as biomarkers. We additionally focus on the use of proteomic techniques in research and evaluate their usefulness in clinical setting.

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Contemporary proteomic strategies for clinical epigenetic research and potential impact for the clinic

Hudler¹,

Paska

Komel³

2015

Expert Review of Proteomics

View full text Add to dashboard Cite

show abstract

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Genetic Testing, an Optimal Strategy for Lynch Syndrome Identification

Cited by 1 publication

References 123 publications

Contemporary proteomic strategies for clinical epigenetic research and potential impact for the clinic

Contemporary proteomic strategies for clinical epigenetic research and potential impact for the clinic

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