Genetic similarity of Puumala viruses found in Finland and western Siberia and of the mitochondrial DNA of their rodent hosts suggests a common evolutionary origin

Dekonenko, Alexander; Yakimenko, V. V.; Ivanov, Alexander P.; Морозов, В. Г.; Nikitin, Pavel A.; Khasanova, Samara; Dzagurova, Tamara K.; Ткаченко, Е. А.; Schmaljohn, Connie S.

doi:10.1016/s1567-1348(03)00088-1

Cited by 55 publications

(52 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Viruses of Russian origin formed several separate lineages such as those found in Omsk and in the Volga River area. These findings provide insight towards understanding the evolution of PUUV [4,22,37].…”

Section: Discussionmentioning

confidence: 74%

“…ern Siberia) are more closely related to Finish strains than to the Russian strains isolated from geographically closer regions (e.g., Ufa, Kazan, Udmurtia, or Samara) [4].…”

Section: Discussionmentioning

confidence: 99%

“…, Vyacheslav G. MOROZOV 3) , Takahiro SETO 1) , Yoichi TANIKAWA 1) , Sergey I. KOLOMINOV 3) , Sergey N. BELOV 3) , Ichiro NAKAMURA 4) , Nobuo HASHIMOTO 1) , Alexander E. BALAKIEV 2) , Tamara K. DZAGURNOVA 2) , Nur Hardy bin Abu DAUD 1) , Daisuke MIYASHITA 1) , Olga A. MEDVEDKINA 2) , Mina NAKAUCHI 1) , Mariko ISHIZUKA 1) , Kentaro YOSHII 1) , Kumiko YOSHIMATSU 5) , Jiro ARIKAWA 5) and Ikuo TAKASHIMA 1)…”

unclassified

See 2 more Smart Citations

Epidemiological Study of Hantavirus Infection in the Samara Region of European Russia

et al. 2009

View full text Add to dashboard Cite

ABSTRACT. European Russia is a highly endemic area of hemorrhagic fever with renal syndrome (HFRS), a rodent-borne zoonotic disease, caused by hantaviruses. In total, 145 small mammals of four species (Myodes glareolus, Apodemus flavicollis, A. agrarius, and A. uralensis) were trapped in the Samara region of European Russia in August 2005 and examined for the presence of hantavirus (HV). Anti-HV antibodies were found in six of 68 (8.8%) M. glareolus and in one of 19 (5.3%) A. flavicollis by indirect immunofluorescent antibody assay (IFA). The Puumala virus (PUUV), which is one of the hantavirus species, was detected in the lungs of seven M. glareolus by RT-PCR. The virus S-segment was extremely similar (96.2% to 99.3%) to the sequence found in a fatal case of HFRS in the Samara region. Phylogenetic analyses of S and M segments showed that the Samara PUUVs form a cluster within the Russian Volga lineage and apparently differ from other European PUUVs. Anti-PUUV antibodies were found in blood sera from seven HFRS patients and from one undiagnosed patient from the Samara region, using IFA and an enzyme-linked immunosorbent assay (ELISA). These data suggest that the bank vole M. glareolus is a primary natural reservoir and vector for PUUV, which is the main causative agent of HFRS in humans in the Samara region.KEY WORDS: epidemiology, hantavirus, hemorrhagic fever with renal syndrome, Puumala virus, rodents.J. Vet. Med. Sci. 71(12): 1569-1578, 2009 Hantaviruses belong to the genus Hantavirus, within the family Bunyaviridae, and cause two forms of human illness. These zoonoses include hemorrhagic fever with renal syndrome (HFRS), which occurs in Asia and Europe and is caused by the Hantaan virus (HTNV), Seoul virus (SEOV), Puumala virus (PUUV), Dobrava-Belgrade virus (DOBV), and Amur virus (AMRV). The second form of illness is hantavirus (cardio) pulmonary syndrome (HPS), which occurs in the Americas and is caused by the Sin Nombre virus, Andes virus, and other hantaviruses [13,28,33]. Hantaviruses are transmitted by aerosolized excreta from their natural hosts, mainly rodents of the family Muridae. Particular hantavirus species are usually harbored by a single rodent species, or by a few closely related rodent species, which indicates co-evolution and co-speciation of hantaviruses with their hosts. The virus genome contains three segments of negative-stranded RNA: the large (L) segment encodes a viral RNA-dependent RNA polymerase, the medium (M) segment encodes a glycoprotein precursor, and the small (S) segment encodes a nucleocapsid protein (NP) [34].In

show abstract

Section: Discussionmentioning

confidence: 74%

“…ern Siberia) are more closely related to Finish strains than to the Russian strains isolated from geographically closer regions (e.g., Ufa, Kazan, Udmurtia, or Samara) [4].…”

Section: Discussionmentioning

confidence: 99%

unclassified

See 1 more Smart Citation

Epidemiological Study of Hantavirus Infection in the Samara Region of European Russia

et al. 2009

View full text Add to dashboard Cite

show abstract

“…18 Species identification of Apodemus flavicollis and Apodemus sylvaticus was confirmed by PCR (polymerase chain reaction) targeting the mitochondrial cytochrome b gene and sequencing of PCR products. 19,20 A total of 242 animals were collected, including 131 yellow-necked mouse (A. flavicollis), 53 striped field mouse (Apodemus agrarius), three wood mouse (A. sylvaticus), 43 bank voles (Myodes glareolus), six common shrews (Sorex araneus), four common voles (Microtus arvalis), one field vole (Microtus agrestis), and one common dormouse (Muscardinus avellanarius). Animal experimentation guidelines of the American Society of Mammologists was followed during all animal work.…”

Section: Methodsmentioning

confidence: 83%

Molecular Survey of Zoonotic Agents in Rodents and Other Small Mammals in Croatia

Tadin¹,

Tokarz²,

Markotić³

et al. 2016

The American Society of Tropical Medicine and Hygiene

View full text Add to dashboard Cite

Abstract. Croatia is a focus for many rodent-borne zoonosis. Here, we report a survey of 242 rodents and small mammals, including 43 Myodes glareolus, 131 Apodemus flavicollis, 53 Apodemus agrarius, three Apodemus sylvaticus, six Sorex araneus, four Microtus arvalis, one Microtus agrestis, and one Muscardinus avellanarius, collected at eight sites in Croatia over an 8-year period. Multiplex MassTag polymerase chain reaction (PCR) was used for detection of Borrelia, Rickettsia, Bartonella, Babesia, Ehrlichia, Anaplasma, Francisella tularensis, and Coxiella burnetii. Individual PCR assays were used for detection of Leptospira, lymphocytic choriomeningitis virus, orthopoxviruses, flaviviruses, hantaviruses, and Toxoplasma gondii. Of the rodents, 52 (21.5%) were infected with Leptospira, 9 (3.7%) with Borrelia miyamotoi, 5 (2%) with Borrelia afzelii, 29 (12.0%) with Bartonella, 8 (3.3%) with Babesia microti, 2 (0.8%) with Ehrlichia, 4 (1.7%) with Anaplasma, 2 (0.8%) with F. tularensis, 43 (17.8%) with hantaviruses, and 1 (0.4%) with an orthopoxvirus. Other agents were not detected. Multiple infections were found in 32 rodents (13.2%): dual infections in 26 rodents (10.7%), triple infections in four rodents (2.9%), and quadruple infections in two rodents (0.8%). Our findings indicate that rodents in Croatia harbor a wide range of bacteria and viruses that are pathogenic to humans.

show abstract

“…(IV) Samples of A. flavicollis from Turkey (Michaux et al, 2004), A. sylvaticus from Russia (Dekonenko et al, 2003), and A. fulvipectus from Georgia (new material and Hille et al, 2002). This last sample is not included in the molecular phylogenetic analyses as the sequence was short (246 bp).…”

Section: Molecular Phylogenymentioning

confidence: 99%

False phylogenies on wood mice due to cryptic cytochrome-b pseudogene

Dubey¹,

Michaux²,

Brünner³

et al. 2009

Molecular Phylogenetics and Evolution

View full text Add to dashboard Cite

a b s t r a c tThe phylogeny and phylogeography of the Old World wood mice (subgenus Sylvaemus, genus Apodemus, Muridae) are well-documented. Nevertheless, the distributions of species, such as A. fulvipectus and A. ponticus remain dubious, as well as their phylogenetic relationships with A. sylvaticus. We analysed samples of Apodemus spp. across Europe using the mitochondrial cytochrome-b gene (cyt-b) and compared the DNA and amino-acid compositions of previously published sequences. The main result stemming from this study is the presence of a well-differentiated lineage of Sylvaemus including samples of various species (A. sylvaticus, A. fulvipectus, A. ponticus) from distant locations, which were revealed to be nuclear copies of the mitochondrial cyt-b. The presence of this cryptic pseudogene in published sequences is supported by different pathways. This has led to important errors in previous molecular trees and hence to partial misinterpretations in the phylogeny of Apodemus.

show abstract

Genetic similarity of Puumala viruses found in Finland and western Siberia and of the mitochondrial DNA of their rodent hosts suggests a common evolutionary origin

Cited by 55 publications

References 40 publications

Epidemiological Study of Hantavirus Infection in the Samara Region of European Russia

Epidemiological Study of Hantavirus Infection in the Samara Region of European Russia

Molecular Survey of Zoonotic Agents in Rodents and Other Small Mammals in Croatia

False phylogenies on wood mice due to cryptic cytochrome-b pseudogene

Contact Info

Product

Resources

About