Abstract:By isoelectric focusing in a pH range of pH 3.5 – 9.5 or of pH 5–8, and by using a functional or an immunological detection, a genetic polymorphism of plasminogen can be demonstrated. In Caucasoids, 2 common alleles – PLG*A (frequency 0.67) and PLG*B (frequency 0.30) – as well as several rare variants (sum of their frequencies 0.03) exist. Systematic studies on the functional activity of the various plasminogen gene products should be performed in order to analyse whether or not a difference of plasminogen act… Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.