Genetic Networks That Govern Sexual Reproduction in the Pezizomycotina

Wilson, Andrea M.; Wilken, P. Markus; Wingfield, Michael J.; Wingfield, Brenda D.

doi:10.1128/mmbr.00020-21

Cited by 19 publications

(25 citation statements)

References 208 publications

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“…with two nonallelic forms, the MAT1-1 and MAT1-2 idiomorphs (Turgeon & Yoder, 2000;Yoder et al, 1986). Based on genome sequences, heterothallic species residing in Calonectria have commonly been found to harbour the MAT1-1-1, MAT1-1-2, and MAT1-1-3 genes in the MAT1-1 idiomorph, and the MAT1-2-1 and MAT1-2-13 genes in the MAT1-2 idiomorph Malapi-Wight et al, 2019;Wilson et al, 2021). (2021) showed that the MAT1-2 mating type was present in isolates from every continent sampled.…”

Section: Ta B L E 1 (Continued)mentioning

confidence: 99%

“…Sexual reproduction in Calonectria is based on a bipolar mating system, controlled by mating type ( MAT ) genes that are found at a single MAT locus ( MAT1 ) with two nonallelic forms, the MAT1‐1 and MAT1‐2 idiomorphs (Turgeon & Yoder, 2000 ; Yoder et al, 1986 ). Based on genome sequences, heterothallic species residing in Calonectria have commonly been found to harbour the MAT1‐1‐1 , MAT1‐1‐2 , and MAT1‐1‐3 genes in the MAT1‐1 idiomorph, and the MAT1‐2‐1 and MAT1‐2‐13 genes in the MAT1‐2 idiomorph (Li et al, 2020 ; Malapi‐Wight et al, 2019 ; Wilson et al, 2021 ).…”

Section: Population Genetics and The Disease Cyclementioning

confidence: 99%

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Calonectria in the age of genes and genomes: Towards understanding an important but relatively unknown group of pathogens

Wingfield

Chen

2022

Molecular Plant Pathology

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The genus Calonectria includes many aggressive plant pathogens causing diseases on various agricultural crops as well as forestry and ornamental tree species. Some species have been accidentally introduced into new environments via international trade of putatively asymptomatic plant germplasm or contaminated soil, resulting in significant economic losses. This review provides an overview of the taxonomy, population biology, and pathology of Calonectria species, specifically emerging from contemporary studies that have relied on DNA‐based technologies. The growing importance of genomics in future research is highlighted. A life cycle is proposed for Calonectria species, aimed at improving our ability to manage diseases caused by these pathogens.

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Section: Ta B L E 1 (Continued)mentioning

confidence: 99%

Section: Population Genetics and The Disease Cyclementioning

confidence: 99%

Calonectria in the age of genes and genomes: Towards understanding an important but relatively unknown group of pathogens

Wingfield

Chen

2022

Molecular Plant Pathology

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“…To this end, conidia and ascospores are formed respectively (Krijgsheld et al, 2013). Over the past few decades, considerable knowledge has been accumulated on the development of conidia and ascospores as well as the mechanism of their generation in Aspergillus (Clutterbuck, 1969; Ojeda‐Lopez et al, 2018; Park & Yu, 2012; Wilson et al, 2021).…”

Section: Introductionmentioning

confidence: 99%

Mrada3 is required for sexual reproduction and secondary metabolite production in industrial fungi Monascus strain

Gao

Song

Zhang

et al. 2022

Journal of Applied Microbiology

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Aims: Monascus spp. are valuable industrial fungi for producing beneficial compounds. Because sporulation is often coupled with the production of secondary metabolites, the current study was performed to investigate how Mrada3 regulated asexual and sexual development and the production of edible pigments and mycotoxin. Methods and Results:The functional characteristics of Mrada3 were identified by gene deletion and overexpression in Monascus ruber M7 (the wild-type, WT).The results revealed that the ΔMrada3 strain aborted sexual development, but it produced many more conidia than WT. RNA-seq data showed that the deletion of Mrada3 altered the expression levels of partial genes involved in sexual and asexual development. In addition, the deletion of Mrada3 also resulted in slower growth, lower pigment production and increased citrinin yield during the late period. For the Mrada3-overexpressed strain, the number of ascospores and pigment content were significantly higher than those of WT, but citrinin was slightly lower than that of WT. Conclusions:The Mrada3 gene plays a vital role in the sporulation development and secondary metabolism of Monascus species.Significance and impact of the study: Mrada3 is first identified as an essential regulator for sexual development in Monascus species, enriching the regulatory knowledge of sexual development in filamentous fungi.

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“…In heterothallic species such as H. omanensis and H. bhutanensis , individuals harbour either the MAT1-1 or MAT1-2 idiomorph, which confer the MAT1-1 and MAT1-2 mating types, respectively (Wilson et al 2015 , 2021a ). Sexual development consequently requires an interaction between two individuals of opposite mating type, as in other heterothallic ascomycetes (Wilson et al 2021b ). In contrast, only MAT1-2 isolates of H. moniliformis and H. fecunda have been discovered and despite the absence of the MAT1-1 mating type, these species are capable of independent sexual reproduction via the unisexual pathway (Liu et al 2018 ; Wilson et al 2015 ).…”

Section: Introductionmentioning

confidence: 99%