Genetic Markers of Immunoglobulins in the Two Orangutan Subspecies and Their Hybrids

Dugoujon, Jean‐Michel; Blanc, Marie-Odile; McClure, Harold M.; Lockwood, E.

doi:10.1159/000156161

Cited by 9 publications

(8 citation statements)

References 13 publications

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“…It is striking to see that we can distinguish the Bornean and Sumatran orangutans [Dugoujon et al, 1984], support ing the evidence from chromosomal studies [Seuanez et al, 1979], Two phenotypes, par ticularly Gm ( 1,17; 10,11,13,15,28) observed in most of the gorillas and all the P. paniscus, and Gm ( 1,17; 10,11,13,15) in some P. troglo dytes, are identical with some homozygotic conditions in humans. Furthermore, another phenotype Gm (l,17;10,11,13,14,28), also common in chimpanzees, is comparable to a human haplotype (though with G3m(5) in addition), which is very frequent in some populations.…”

Section: Discussionmentioning

confidence: 99%

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Evolution of Immunoglobulin Allotypes and Phylogeny of Apes

Dugoujon

Hazout²

1987

IJFP

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Serum samples from 72 Pan troglodytes, 5 Pan paniscus, 22 Gorilla gorilla, 23 Pongo pygmaeus abelii, 5 Pongo pygmaeus pygmaeus, 2 hybrids P.p. abelii × P.p. pygmaeus and 13 Hylobates for were tested for Gm(1, 2, 3, 5, 6, 10, 11, 13, 14, 15, 16, 17, 21, 24, 28), Km(1) and Bm(1, 2, 3, 4, 5, 6, 7, 8) immunoglobulin allotypes by the classical hemagglutination inhibition method. The distribution of the various alleles and phenotypes makes it possible to distinguish each species or subspecies. Common chimpanzees have the richest polymorphism. Pygmy chimpanzees share common phenotypes with gorillas. Bornean and Sumatran orangutans have their own patterns of polymorphism, as do gibbons. Our principal component plot and dendrogram are compatible with the traditional classification of Hominoidea [e.g. Simpson, Bull. Am. Mus. nat. Hist. 85: 1–350, 1945] in 3 families: Hom-inidae, Pongidae and Hylobatidae.

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Section: Discussionmentioning

confidence: 99%

“…The classical hemagglutination inhibition method on opaline plates was used [Dugoujon et al, 1984]. The reagents used for Gm and Km determination were of human origin (table II).…”

Section: Methodsmentioning

confidence: 99%

Evolution of Immunoglobulin Allotypes and Phylogeny of Apes

Dugoujon

Hazout²

1987

IJFP

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“…Relatively few Gm allotypes have been found in the numerous Cercopithecoidea species, notably Glm(a), G3m(b0), (b5), (c5), and (s) in baboons, macaques, and mangabeys, the first two allotypes being polymorphic among african forest Cercopithecines (DuGoUJON et al, 1989). All the P. cynocephalus studied by STEINBERG et al (1977) were G3m(c5) negative.…”

Section: Gm Km and Am Polymorphismsmentioning

confidence: 99%

“…comm. DUGOUJON et al, 1984DtJGotJ~o~ & HAzot~r, 1987DUGOUJON et al, 1984DUGOUJON & HAZOUT, 1987DUGOUJON et al, 1984DUGOUJON & HAZOUT, 1987ALEPA, 1969LITWIN, 1969GAARDER & NATVIG, 1974VAN LOGHEr~I et al, 1968VAN LOGHEM & LITWlN, 1972;SHUSTER et a[., 1970VAN LOGHEM & DE LANGs 1979SHANFIELD, pers. comm.…”

Section: Localization Of Gm Antigensmentioning

confidence: 99%

“…comm. STEINBERG et al, 1977DUGOUJON, unpubl, results VAN LOGHEM & DE LANGE, 1979DUGOUJON, unpubl, results DUGOUJON, unpubl, results GAAROER & NArVlG, 1974VAN LOGHe~a & LtrwIN, 1972;SHUSTER et al, 1970 DUGOUJON, unpubl, results (continued) VAN LOGHEM et al, 1968W,N LOGHEM & LITWlI'4, 1972;SHOSrER et al, 19700 VAN LOGHErq & oE L,~GE, 1979DUGOUJON et al, 1989DUGOUJON et al, 1989DUGOUJON et al, 1989DUGOUJON et al, 1989DUGOUJON et al, 1989DUGOUJON et al, 1989DUGOUJON et al, 1989DUGOUJON et al, 1989DU6OUJON et al, 1989DUGOUJON et al, 1989DUGOUJON el aL, 1989DU6OUJON et al, 1989DUGOUJON et al, 1989 (continued) , 1989DUGOUJON et al, 1989DUGOUJON et al, 1989DUGOUJON et al, 1989DUGOUJON et al, 1989DUGOUJON et al, 1989DUGOUJON et al, 1989DUGOUJON et al, 1989 DUGOUION, unpubl, results Du~oUJON, unpubl, results DUGOUJON et al, 1989LtTwm, 1969Rw~,T et al, 1968GAARDER & NATVIG, 1974VAN LOGHEM et al, 1968VaN LOGHEr, I & LITWIN, 1972;SHUSTER et al, 1970VAN LOBHEM & DE D, NGE, 1979DUGOUJON et al, 1989DUGOUJON et al, 1989LITWIN, 1969RIVAT et al, 1968VAN LOGHEM et al, 1968 …”

Section: Localization Of Gm Antigensmentioning

confidence: 99%

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Immunoglobulin allotypes (Gm, Am, and Km) in non-human primates

Dugoujon

1993

Primates

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ABSTRACT. The immunoglobulin (lg) allotypes (Gm, Am, and Km systems) are the genetic markers of the human IgG1, IgG2, IgG3(Gm), lgA2(Am), and kappa light chain(Km). The Gm system, with 18 allotypes shows the greatest degree of polymorphism and we define two Am and three Km allotypes.In this review, we report all the results observed in non-human primates belonging to Hominoidea, Cercopithecoidea, Ceboidea, Lorisoidea, Lemuroidea, and Tupaoidea superfamilies (72 species and subspecies). They concern published data and new unpublished ones. The distribution of the human allotypes and their localization are reported, as well as discordant results observed in some cases with anti-allotype reagents of the same specificity (human and animal origin).Some allotypes are restricted to man. Hominoidea have the greatest number of Gm allotypes and the richest polymorphism. Relatively few allotypes have been found in Cercopithecoidea and Prosimians; most Platyrrhinian species have no allotype. The epitopic polymorphism has been interpreted in terms of evolution of Ig allotypes from primate to man and of the phylogenetic relationships of non-human primate species.

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Call diversity of wild male orangutans: a phylogenetic approach

Davila‐Ross

Geissmann²

2006

American J Primatol

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Over the past 20 years several studies have attempted to clarify orangutan systematics based on DNA sequences and karyological and morphological data; however, the systematic and phylogenetic relationships among orangutan taxa remain controversial. Surprisingly, few systematic studies have used data from wild-living orangutans of exactly known provenance. Furthermore, most of these studies pooled data from huge geographic areas in their analyses, thus ignoring possibly distinct subpopulations. This study represents a new approach to orangutan systematics that uses orangutan long calls. Long calls are species-specific vocalizations used by many nonhuman primates, and data on their acoustical and temporal structures have been used to assess the relationships among, and phylogenies of, several primate taxa. Altogether, 78 long calls from wild-living orangutans from five populations in Borneo and five in Sumatra were included in the analyses. Aside from the chiefly paraphyletic topology of cladistic results, which neither support nor reject a Borneo-Sumatra dichotomy, bootstrap values support three monophyletic clades (northwest Borneo, northeast-east Borneo, and Ketambe) that corroborate geographic groups. The shortest trees and multivariate analyses provide some support for a closer relationship between Sumatran and specific Bornean demes than between particular Bornean demes themselves, indicating that conservation management should be based on orangutans from different populations rather than on just the two island-specific groups.

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Genetic Markers of Immunoglobulins in the Two Orangutan Subspecies and Their Hybrids

Cited by 9 publications

References 13 publications

Evolution of Immunoglobulin Allotypes and Phylogeny of Apes

Evolution of Immunoglobulin Allotypes and Phylogeny of Apes

Immunoglobulin allotypes (Gm, Am, and Km) in non-human primates

Call diversity of wild male orangutans: a phylogenetic approach

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