Genetic diversity study of the yeast Saccharomyces bayanus var. uvarum reveals introgressed subtelomeric Saccharomyces cerevisiae genes

Наумова, Е. С.; Наумов, Г. И.; Michailova, Yulia V.; Мартыненко, Н. Н.; Masneuf‐Pomarède, Isabelle

doi:10.1016/j.resmic.2010.09.023

Cited by 25 publications

(23 citation statements)

References 46 publications

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“…None of the other strains showed evidence of recent interspecific hybridization. Although S. uvarum and S. cerevisiae-S. uvarum hybrids play a role in winemaking (Naumova et al 2011), we saw no evidence for such hybrids or S. uvarum introgression events among our commercial or the wild wine isolates.…”

Section: Interspecific Hybridization and Introgressioncontrasting

confidence: 68%

“…For the two strains with dual species introgression, this implies that progenitors of these strains either (1) successively hybridized with each of the other two species, or (2) hybridized with one of the other species, which already contained the other introgression. In all cases, it appears that the introgressed regions occur near or within subtelomeric regions (Naumova et al 2005(Naumova et al , 2011, and are found among the various strains in either homozygous (lacking equivalent S. cerevisiae sequences) or hemizygous states.…”

Section: Interspecific Hybridization and Introgressionmentioning

confidence: 95%

“…Furthermore, introgression events, defined as a relatively small region of a different species' genome found within the genome of another species and mostly occurring within the closely related species of the Saccharomyces sensu stricto group, have also been detected (Naumova et al 2005;Liti et al 2006;Doniger et al 2008;Muller and McCusker 2009a,b;Naumova et al 2011). Horizontal gene transfer, in which genes are transferred from a distantly related organism (even transkingdom) through nonsexual mechanisms, has also been described among the Saccharomyces yeasts (Hall et al 2005;Novo et al 2009;Rolland et al 2009), although it may be relatively rare.…”

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confidence: 99%

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Analysis of the Saccharomyces cerevisiae pan-genome reveals a pool of copy number variants distributed in diverse yeast strains from differing industrial environments

Dunn¹,

Richter²,

Kvitek³

et al. 2012

Genome Res.

202

182

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Although the budding yeast Saccharomyces cerevisiae is arguably one of the most well-studied organisms on earth, the genome-wide variation within this species—i.e., its “pan-genome”—has been less explored. We created a multispecies microarray platform containing probes covering the genomes of several Saccharomyces species: S. cerevisiae, including regions not found in the standard laboratory S288c strain, as well as the mitochondrial and 2-μm circle genomes–plus S. paradoxus, S. mikatae, S. kudriavzevii, S. uvarum, S. kluyveri, and S. castellii. We performed array-Comparative Genomic Hybridization (aCGH) on 83 different S. cerevisiae strains collected across a wide range of habitats; of these, 69 were commercial wine strains, while the remaining 14 were from a diverse set of other industrial and natural environments. We observed interspecific hybridization events, introgression events, and pervasive copy number variation (CNV) in all but a few of the strains. These CNVs were distributed throughout the strains such that they did not produce any clear phylogeny, suggesting extensive mating in both industrial and wild strains. To validate our results and to determine whether apparently similar introgressions and CNVs were identical by descent or recurrent, we also performed whole-genome sequencing on nine of these strains. These data may help pinpoint genomic regions involved in adaptation to different industrial milieus, as well as shed light on the course of domestication of S. cerevisiae.

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Section: Interspecific Hybridization and Introgressioncontrasting

confidence: 68%

Section: Interspecific Hybridization and Introgressionmentioning

confidence: 95%

mentioning

confidence: 99%

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Analysis of the Saccharomyces cerevisiae pan-genome reveals a pool of copy number variants distributed in diverse yeast strains from differing industrial environments

Dunn¹,

Richter²,

Kvitek³

et al. 2012

Genome Res.

202

182

View full text Add to dashboard Cite

show abstract

“…This phenomenon was mentioned a few years ago for Saccharomyces, based on classical molecular genetic methods (32,148), and was recently extended using microsatellite typing (149). With complete genome sequences, introgression of delineated chromosomal fragments from one yeast species to another appears more frequent than initially anticipated.…”

Section: Traces Of Natural Introgressions In Yeast Genomesmentioning

confidence: 97%

“…Genome data are also particularly powerful for reconstructing phylogenies, one of the criteria used to define species in addition to the classical morphological and biological criteria (214). These data, although still limited relative to the large number of extant yeast isolates (101), were already sufficient to reveal the presence of introgressions between distantly related species (95,141,149,159), as well as the existence of natural hybrid genomes at various stages in their evolution (12,43,105,164).…”

Section: Introductionmentioning

confidence: 99%

Evolutionary Role of Interspecies Hybridization and Genetic Exchanges in Yeasts

Morales

Dujon

2012

Microbiol Mol Biol Rev

153

158

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SUMMARYForced interspecific hybridization has been used in yeasts for many years to study speciation or to construct artificial strains with novel fermentative and metabolic properties. Recent genome analyses indicate that natural hybrids are also generated spontaneously between yeasts belonging to distinct species, creating lineages with novel phenotypes, varied genetic stability, or altered virulence in the case of pathogens. Large segmental introgressions from evolutionarily distant species are also visible in some yeast genomes, suggesting that interspecific genetic exchanges occur during evolution. The origin of this phenomenon remains unclear, but it is likely based on weak prezygotic barriers, limited Dobzhansky-Muller (DM) incompatibilities, and rapid clonal expansions. Newly formed interspecies hybrids suffer rapid changes in the genetic contribution of each parent, including chromosome loss or aneuploidy, translocations, and loss of heterozygosity, that, except in a few recently studied cases, remain to be characterized more precisely at the genomic level by use of modern technologies. We review here known cases of natural or artificially formed interspecies hybrids between yeasts and discuss their potential importance in terms of genome evolution. Problems of meiotic fertility, ploidy constraint, gene and gene product compatibility, and nucleomitochondrial interactions are discussed and placed in the context of other known mechanisms of yeast genome evolution as a model for eukaryotes.

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The ecology and evolution of non-domesticatedSaccharomycesspecies

Boynton

Greig

2014

Yeast

103

109

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Yeast researchers need model systems for ecology and evolution, but the model yeast Saccharomyces cerevisiae is not ideal because its evolution has been affected by domestication. Instead, ecologists and evolutionary biologists are focusing on close relatives of S. cerevisiae, the seven species in the genus Saccharomyces. The best-studied Saccharomyces yeast, after S. cerevisiae, is S. paradoxus, an oak tree resident throughout the northern hemisphere. In addition, several more members of the genus Saccharomyces have recently been discovered. Some Saccharomyces species are only found in nature, while others include both wild and domesticated strains. Comparisons between domesticated and wild yeasts have pinpointed hybridization, introgression and high phenotypic diversity as signatures of domestication. But studies of wild Saccharomyces natural history, biogeography and ecology are only beginning. Much remains to be understood about wild yeasts' ecological interactions and life cycles in nature. We encourage researchers to continue to investigate Saccharomyces yeasts in nature, both to place S. cerevisiae biology into its ecological context and to develop the genus Saccharomyces as a model clade for ecology and evolution. © 2014 The Authors. Yeast published by John Wiley & Sons Ltd.

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Genetic diversity study of the yeast Saccharomyces bayanus var. uvarum reveals introgressed subtelomeric Saccharomyces cerevisiae genes

Cited by 25 publications

References 46 publications

Analysis of the Saccharomyces cerevisiae pan-genome reveals a pool of copy number variants distributed in diverse yeast strains from differing industrial environments

Analysis of the Saccharomyces cerevisiae pan-genome reveals a pool of copy number variants distributed in diverse yeast strains from differing industrial environments

Evolutionary Role of Interspecies Hybridization and Genetic Exchanges in Yeasts

The ecology and evolution of non-domesticatedSaccharomycesspecies

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