Genetic Disease

Khoury, Muin J.; Dorman, Janice S.

doi:10.1016/b978-0-08-092566-0.50018-5

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Origins Of Caste Evolution1

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1996

2002

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“…The penetrance of the genotype depends upon other vectors as well, such as environmental factors. Because of adaptive mechanisms, including environmental controls, negative natural selection need not occur at all (6).…”

Section: Origins Of Caste Evolutionmentioning

confidence: 99%

A moral history of the evolution of a caste of workers.

Samuels¹

1996

Environ Health Perspect

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Using a dialectic method of philosophic inquiry, the actual ethical, legal, and social situation associated with genetic testing of beryllium-exposed workers in Department of Energy nuclear weapons facilities for markers of chronic beryllium disease is described. The cultural evolution of a caste system in a similar situation, and its social and biological implications, among uranium miners in the Erz Gebirge of Central Europe and on the Colorado Plateau of the United States, marked by suicide and lung disease, including cancer, is also described. The historically persistent social disease resulting from these situations. The Masada Syndrome, named from an analogous situation in biblical times, is characterized. Cultural intervention, a necessary condition for the ethical progression of the Human Genome Project, is outlined.

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Section: Origins Of Caste Evolutionmentioning

confidence: 99%