Genetic Classification of “Norwalk‐like Viruses”

Ando, Tamie; Noel, Jacqueline S.; Fankhauser, Rebecca L.

doi:10.1086/315589

Cited by 275 publications

(240 citation statements)

References 84 publications

Supporting

Mentioning

226

Contrasting

Unclassified

Order By: Relevance

“…Antigenic and genetic variability is also a feature of other caliciviruses, especially the human noroviruses, where highly variable genogroups containing multiple genotypes are described [2,34]. The origins of this diversity are poorly understood.…”

Section: Aetiologymentioning

confidence: 99%

Feline calicivirus

et al. 2007

View full text Add to dashboard Cite

-Feline calicivirus (FCV) is an important and highly prevalent pathogen of cats. It belongs to the family Caliciviridae which includes other significant pathogens of man and animals. As an RNA virus, high polymerase error rates convey upon FCV a high genome plasticity, and allow the virus to respond rapidly to environmental selection pressures. This makes the virus very adaptable and has important implications for clinical disease and its control. Being genetically diverse, FCV is associated with a range of clinical syndromes from inapparent infections to relatively mild oral and upper respiratory tract disease with or without acute lameness. More recently, highly virulent forms of the virus have emerged associated with a systemic infection that is frequently fatal. A proportion of FCV infected cats that recover from acute disease, remain persistently infected. In such cats, virus evolution is believed to help the virus to evade the host immune response. Such longterm carriers may only represent a minority of the feline population but are likely to be crucial to the epidemiology of the virus. Vaccination against FCV has been available for many years and has effectively reduced the incidence of clinical disease. However, the vaccines do not prevent infection and vaccinated cats can still become persistently infected. In addition, FCV strain variability means that not all strains are protected against equally. Much progress has been made in understanding the biology and pathogenesis of this important feline virus. Challenges for the future will necessarily focus on how to control the variability of this virus particularly in relation to emerging virulent strains and vaccination.

show abstract

Section: Aetiologymentioning

confidence: 99%

Feline calicivirus

et al. 2007

View full text Add to dashboard Cite

show abstract

“…Recently, Ando et al [1] have proposed a genetic classification of human NLVs into 2 major genetic groups, genogroups GI and GII, consisting of 5 and 10 genetic clusters, respectively. In addition, they described a third genogroup, including 2 bovine strains, the Newbury Agent-2 (NA-2) and Jena/80 (JV).…”

Section: Introductionmentioning

confidence: 99%

“…The aim of the present study was to provide a genetic classification of SLV strains, using the same criteria and methodology as Ando et al [1] for their classification of NLVs. We sequenced 3-kb of the 3 half of the genome of 2 SLV strains detected in French infants and analysed these newly determined sequences, The SLV strains sequenced in this study are highlighted in bold.…”

Section: Introductionmentioning

confidence: 99%

Genetic classification of "Sapporo-like viruses"

Schuffenecker

Ando

Thouvenot

et al. 2001

Archives of Virology

Self Cite

View full text Add to dashboard Cite

“…Human NVs can be divided into two genogroups, genogroups GI and GII, by genetic analysis of the RNA polymerase and capsid regions (1, 15), with several genotype classifications having been reported independently (1,16,33). Recently, based on the genotype classification of Katayama et al (16), Kageyama et al (15) reported on a detailed scheme for the genotyping of NVs based on distribution analysis by using the pairwise distance of the capsid N-terminal/shell domain.…”

mentioning

confidence: 99%

Genetic Analysis of Noroviruses in Chiba Prefecture, Japan, between 1999 and 2004

et al. 2005

View full text Add to dashboard Cite

Noroviruses (NVs) are common pathogens that consist of genetically divergent viruses that induce gastroenteritis in humans and animals. Between September 1999 and June 2004, 1,898 samples obtained from patients showing sporadic or outbreak gastroenteritis in Chiba Prefecture, Japan, were tested for NVs by reverse transcription-PCR. NVs were detected in 603 samples. Approximately 80% were positive for genogroup GII, 13% were positive for genogroup GI, and the remaining 7% were positive for both genogroups. Phylogenetic analysis showed that the GI and GII genogroups could be further divided into 13 and 16 genotypes (including new genotypes), respectively. The GII-4 genotype, which included five small genetic clusters (subtypes), was the most common in this study and was detected in approximately 40% of positive samples. The P2 regions of 10 strains belonging to each of the five GII-4 subtypes showed 5 to 18% amino acid diversity. The amino acid substitutions accumulated in the protruding (P) region during the 5-year study period. Our data suggest that highly variable NV strains are circulating in Chiba Prefecture, with a high rate of genetic change observed during the 5-year study period.The genus Norovirus is a member of the family Caliciviridae. Caliciviruses contain a positive-sense single-stranded RNA genome and include a further three genera, Vesivirus, Lagovirus, and Sapovirus (2,3,8). Noroviruses (NVs) have three major open reading frames (ORFs) that encode nonstructural, capsid, and minor structural proteins, respectively (8). They are one of the most common causes of gastroenteritis and have been detected in fecal samples from both humans (12,15,28) and animals (20,30,37). Human-associated NV outbreaks resulting from ingestion of contaminated water or food, such as oysters (4,5,18,23), and outbreaks in public places, particularly hospitals, schools, and cruise ships (9,11,22,36), pose an important public health problem.Reverse transcription-PCR (RT-PCR) and sequencing of the partial viral genome are the most popular and useful procedures for obtaining epidemiological and genetic information on NVs. Human NVs can be divided into two genogroups, genogroups GI and GII, by genetic analysis of the RNA polymerase and capsid regions (1, 15), with several genotype classifications having been reported independently (1,16,33). Recently, based on the genotype classification of Katayama et al. (16), Kageyama et al. (15) reported on a detailed scheme for the genotyping of NVs based on distribution analysis by using the pairwise distance of the capsid N-terminal/shell domain. They classified the GI and GII genogroups into 14 and 17 genotypes, respectively.During the winter of 2002-2003, an increase in NV outbreaks was reported in Europe and the United States (6, 21). Moreover, worldwide, the GII-4 genotype (Bristol virus-like genotype) has been shown to be the predominant strain of NV associated with gastroenteritis (13,21,(34)(35)(36). Changes in the phylogenetic and genetic characteristics of GII-4 genotype strains...

show abstract

Genetic Classification of “Norwalk‐like Viruses”

Cited by 275 publications

References 84 publications

Feline calicivirus

Feline calicivirus

Genetic classification of "Sapporo-like viruses"

Genetic Analysis of Noroviruses in Chiba Prefecture, Japan, between 1999 and 2004

Contact Info

Product

Resources

About