2022
DOI: 10.1002/ajpa.24620
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Genetic characterization of two North Italian villages: A story of isolation, ancient admixture, and genetic drift

Abstract: Objectives Population isolates represent a focus of interest because of their particular genetic history and the possibility of mapping peculiar deleterious variants. Here we investigated the pattern of genetic variation in two North Italian villages: Rotzo (RTZ) and Stoccareddo (STC), in the Asiago plateau. Materials and methods We genotyped over 800 individuals for more than 600.000 markers. We investigated the isolation level by analyzing runs of homozygosity (ROH) and the level of population structure. The… Show more

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