Genetic characterization of Tibetan pigs adapted to high altitude under natural selection based on a large whole-genome dataset
Lingyun Zhang,
Yanbin Zhu,
Yue Ren
et al.
Abstract:The Qinghai-Tibet Plateau is a valuable genetic resource pool, and the high-altitude adaptation of Tibetan pigs is a classic example of the adaptive evolution of domestic animals. Here, we report the presence of Darwinian positive selection signatures in Tibetan pigs (TBPs) using 348 genome-wide datasets (127 whole-genome sequence datasets (WGSs) and 221 whole-genome single-nucleotide polymorphism (SNP) chip datasets). We characterized a high-confidence list of genetic signatures related response to high-altit… Show more
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