Genetic characterization of the domestic pig (Sus scrofa domestica) in Cerete-Colombia, using microsatellite markers

G, Iván Meléndez; P, Enrique Pardo; M, Teodora Cavadia

doi:10.21897/rmvz.108

Cited by 5 publications

(3 citation statements)

References 17 publications

(22 reference statements)

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“…Also, genetic diversity was examined in some populations using a high-density panel of SNPs [8]. Studies with microsatellites markers have also been reported on some Criollo populations, but were limited to a relatively small number of breeds, or restricted to animals from particular countries or regions [12,[43][44][45][46][47][48][49][50][51][52][53][54].…”

Section: Discussionmentioning

confidence: 99%

On the origins of American Criollo pigs: A common genetic background with a lasting Iberian signature

et al. 2021

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American Criollo pigs are thought to descend mainly from those imported from the Iberian Peninsula starting in the late 15th century. Criollo pigs subsequently expanded throughout the Americas, adapting to very diverse environments, and possibly receiving influences from other origins. With the intensification of agriculture in the mid-20th century, cosmopolitan breeds largely replaced Criollo pigs, and the few remaining are mostly maintained by rural communities in marginal areas where they still play an important socio-economic and cultural role. In this study, we used 24 microsatellite markers in samples from 1715 pigs representing 46 breeds with worldwide distribution, including 17 American Criollo breeds, with the major focus of investigating their genetic diversity, structure and breed relationships. We also included representatives of the Iberian, Local British, Hungarian, Chinese and Commercial breeds, as well as Wild Boar, in order to investigate their possible influence in the genetic composition of Criollos. Our results show that, when compared with the other breeds, Criollo pigs present higher levels of genetic diversity, both in terms of allelic diversity and expected heterozygosity. The various analyses indicate that breed differentiation overall explains nearly 21% of the total genetic diversity. Criollo breeds showed their own identity and shared a common genetic background, tending to cluster together in various analyses, even though they differ from each other. A close relationship of Criollos with Iberian breeds was revealed by all the different analyses, and the contribution of Iberian breeds, particularly of the Celtic breeds, is still present in various Criollo breeds. No influence of Chinese breeds was detected on Criollos, but a few were influenced by Commercial breeds or by wild pigs. Our results confirm the uniqueness of American Criollo pigs and the role that Iberian breeds have played in their development.

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Section: Discussionmentioning

confidence: 99%

On the origins of American Criollo pigs: A common genetic background with a lasting Iberian signature

et al. 2021

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“…However, this has not yet been done in CR pigs. As in many other local breeds, the rst attempts to genetically characterize CR local breeds were based on a small set of neutral markers such as microsatellites (Oslinger et al, 2006;Meléndez et al, 2015), but their relationship with relevant traits is not straightforward (Kirk & Freeland, 2011).…”

Section: Introductionmentioning

confidence: 99%

Identification of breed-specific genomic variants in Colombian Creole pig breeds by whole-genome sequencing

Suárez-Mesa

Ros‐Freixedes

Laghouaouta

et al. 2022

Preprint

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Dissecting genetic variation of local breeds is important for the success of conservation. In this research, we investigated the genomic variation of Colombian Creole (CR) pigs, with a focus on the breed-specific variants in the exonic region of 34 genes with reported effects on adaptive and economical traits. Seven individuals of each of the three CR breeds (CM: Casco de Mula; SP: San Pedreño; and ZU: Zungo) were whole-genome sequenced along with seven Iberian (IB) pigs and seven pigs of each of the four most used cosmopolitan (CP) breeds (Duroc, Large White × Landrace, and Pietrain). Molecular variability in CR (6,451,218 variants; from 3,919,242, in SP, to 4,648,069, in CM) was comparable to that in CP, but higher than in IB. For the investigated genes, SP pigs displayed less exonic variants (178) than ZU (254), CM (263), IB (200), and the individual CP genetic types (201 to 335). Sequence variation at these genes confirmed the resemblance of CR to IB, but also that CR, particularly ZU and CM, are not exempt from selective introgression of other breeds. A total of 50 exonic variants were identified as being potentially specific to CR, including a high-impact deletion in the intron between exons 15 and 16 of the leptin receptor gene that is only present in CM and ZU. The identification of breed-specific variants in genes related to adaptive and economical traits can bolster the understanding of the role of gene-environment interactions on local adaptation and points the way for effective breeding and conservation of CR pigs.

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“…The different breeds used in the modern pig industry have a greater impact on the rural economy because they are considered a low-cost protein source 31 , 32 . The appearance of the domestic pig in America arose from the introduction of Iberian or hairless pigs during the time of the Conquest; they have become adapted to local conditions over a period lasting more than 500 years, having some special phenotypical characteristics 31 , 33 . Three breeds are currently located in specific areas of Colombia.…”

Section: Introductionmentioning

confidence: 99%

A comparative analysis of SLA-DRB1 genetic diversity in Colombian (creoles and commercial line) and worldwide swine populations

Celis-Giraldo

Bohórquez

Camargo

et al. 2021

Sci Rep

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Analysing pig class II mayor histocompatibility complex (MHC) molecules is mainly related to antigen presentation. Identifying frequently-occurring alleles in pig populations is an important aspect to be considered when developing peptide-based vaccines. Colombian creole pig populations have had to adapt to local conditions since entering Colombia; a recent census has shown low amounts of pigs which is why they are considered protected by the Colombian government. Commercial hybrids are more attractive regarding production. This research has been aimed at describing the allele distribution of Colombian pigs from diverse genetic backgrounds and comparing Colombian SLA-DRB1 locus diversity to that of internationally reported populations. Twenty SLA-DRB1 alleles were identified in the six populations analysed here using sequence-based typing. The amount of alleles ranged from six (Manta and Casco Mula) to nine (San Pedreño). Only one allele (01:02) having > 5% frequency was shared by all three commercial line populations. Allele 02:01:01 was shared by five populations (around > 5% frequency). Global FST indicated that pig populations were clearly structured, as 20.6% of total allele frequency variation was explained by differences between populations (FST = 0.206). This study’s results confirmed that the greatest diversity occurred in wild boars, thereby contrasting with low diversity in domestic pig populations.

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Genetic characterization of the domestic pig (Sus scrofa domestica) in Cerete-Colombia, using microsatellite markers

Cited by 5 publications

References 17 publications

On the origins of American Criollo pigs: A common genetic background with a lasting Iberian signature

On the origins of American Criollo pigs: A common genetic background with a lasting Iberian signature

Identification of breed-specific genomic variants in Colombian Creole pig breeds by whole-genome sequencing

A comparative analysis of SLA-DRB1 genetic diversity in Colombian (creoles and commercial line) and worldwide swine populations

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