Genetic characterization of bank vole virus (BaVV), a new paramyxovirus isolated from kidneys of bank voles in Russia

Abstract

A genome of bank vole virus (BaVV), isolated from kidney tissues of bank voles (Myodes glareolus) in Russia in 1973, was sequenced. The genomic organization of BaVV (3'-N-P/V/C-M-F-G-L-5', 16,992 nt in length; GenBank accession number MF943130) is most similar to that of Mossman virus (MoV) and Nariva virus (NarPV), two ungrouped paramyxoviruses isolated from rodents in Australia and Trinidad, respectively. The proteins of BaVV have the highest level of sequence identity (ranging from 23-28% for G protein to 66-73% for M protein) to proteins of MoV and NarPV. The results of genetic and phylogenetic analysis suggest that BaVV represents a new species and, together with MoV and NarPV, belongs to a new, yet not established genus of the family Paramyxoviridae.

Infection Load and Prevalence of Novel Viruses Identified from the Bank Vole Do Not Associate with Exposure to Environmental Radioactivity

“…We identified four new bank vole virus genomes from three families, increasing the known diversity of viruses in bank voles to nearly 20 species [1,[6][7][8][9][10][11][12][13][14][15][16]. The new virus genomes were not endemic to Ukraine, but were present also in Swedish bank voles, raising the possibility that these viruses are present in bank voles throughout much of their geographic range.…”

“…The bank vole (Myodes glareolus), a small rodent that is common in woodland habitats throughout much of Europe and northwest Asia, is an zoonotic hyper-reservoir [3]. Bank voles host disease-causing viruses such as Puumala hantavirus [4], flavivirus tick borne encephalitis virus [5], orthonairovirus Crimean-Congo hemorrhagic fever virus [6], cowpox virus [7], and picornavirus Ljungan virus [8]; moreover, bank voles harbor paramyxoviruses [9,10], alphacoronaviruses [11], polyomaviruses [12], herpesviruses [13,14], anelloviruses [15], and hepaciviruses [16]. As bank voles host a diverse and important viral community, this species is an ideal model in which to study the potential effects of environmental factors on virus community and population dynamics.…”

Discovery and Prevalence of Divergent RNA Viruses in European Field Voles and Rabbits

“…In every gene analyzed this virus clustered with narmoviruses that had been isolated from a range of rodents from diverse locations globally. Specifically, other viruses within this clade were identified in bank voles from Russia [33], wild rats in Australia [34] and common cane mice in Trinidad [35]. Such a phylogenetic pattern suggests that rodent narmoviruses are temporally and spatially widespread and arose from a single common ancestor, although this will need to be confirmed with a larger sample of viruses.…”

Taxonomy of the order Mononegavirales: update 2019

“…1 Includes Newcastle disease virus (NDV). 2 Due to a formal classification mistake, this species was incorrectly named Synodus paramyxovirus in 2019. A proposal to change the species name to the correct "Synodus synodonvirus" will be submitted prior to the next taxonomic proposal submission deadline.…”