Genetic characterization and evolutionary analysis of canine parvovirus in Tangshan, China

Molecular characterization of canine parvovirus type 2 (CPV2) reveals a high prevalence of the CPV2c genotype among dogs suffering from diarrhea

“…1), suggesting a close phylogenetic relationship. Several reports agree with our findings, which suggest an increasing number of cases of CPV-2c in China in recent years (Wang et al 2016(Wang et al , 2022Wu et al 2018;Hao et al 2020Hao et al , 2022Hu et al 2020;Qi et al 2020;Chen et al 2021;Jiang et al 2021;Liu et al 2021;Fu et al 2022;Jing et al 2022). Recently, Liu reported a positive detection rate of 40.78% (84/206) and a predominance of CPV-2c in Shanghai in 2020 (Liu et al 2021).…”

“…During the last decade, the Asian lineage of CPV-2c has spread worldwide, including Africa, USA, South America, and European countries (France, Italy and Germany), and is no longer considered to be Asian (Franzo et al 2023). Until 2015, the genotypes CPV-2a and CPV-2b remained predominant in China, although an increasing number of cases of CPV-2c were reported in Europe and the Americas (Zhao et al 2013(Zhao et al , 2017Zhong et al 2014;Zhou et al 2016;Wu et al 2018;Li et al 2019;Qi et al 2020;Chen et al 2021;Jiang et al 2021;Liu et al 2021;Fu et al 2022;Hao et al 2022;Huang et al 2022;Wang et al 2022). Recently, the incidence of CPV-2 infections associated with CPV-2c genotypes has increased in several provinces of China; seemingly, this new CPV-2c variant is quickly replacing the previous CPV-2a and CPV-2b in China (Hao et al 2020(Hao et al , 2022Hu et al 2020;Qi et al 2020;Chen et al 2021;Fu et al 2022;Jing et al 2022).…”