Abstract:Objective
To investigate the genetic burden in fetuses with isolated and severe fetal growth restriction (FGR) using Trio whole‐exome sequencing (WES) with a normal chromosomal microarray.
Method
This retrospective study analyzed WES results of singleton fetuses with isolated and severe FGR, whose estimated fetal weight (EFW) was less than the third percentile by Hadlock formula, in a tertiary center between March 2016 and March 2022. Cases with abnormal chromosomal microarray analysis (CMA) and TORCH results … Show more
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