Abstract:The integrity of the skin is maintained by complex networks of structural and non‐structural proteins within the epidermis, epidermal basement membrane zone and upper dermis. Disruption to the function of any one of these integral proteins through inherited gene mutations can make the skin less resilient to trauma and more prone to blister formation. This chapter provides an overview of key proteins involved in skin integrity and outlines the spectrum of blistering diseases linked to abnormalities therein. The… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.