Abstract:Bovine mastitis is a host response to the microorganisms linked with the host immune system efficiency. Tumor necrosis factor-alpha (TNF-α) is a proinflammatory cytokine that plays a significant role in the innate and adaptive immune response. In this study, we characterized the upstream regulatory region and evaluated the relative mRNA expression of TNF-α gene of Sahiwal cows. A single nucleotide polymorphism A>G was identified located within a sequence (MT_919286) at the 5´ upstream region. For gene expre… Show more
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