Genetic association of lipids and lipid-lowering drug target genes with sarcoidosis
Wei Tan,
Zicheng Liang,
Yu Liu
et al.
Abstract:Objective:
Todetermine the potential causal association between serum lipid levels and sarcoidosis, and to investigate the potential impact of lipid-lowering agents on sarcoidosis.
Methods:
Two-sample Mendelian randomization (TSMR) was used to investigate the association between lipid levels (including LDL-c, HDL-c, TG, and TC) and sarcoidosis risk. In addition, we conducted a comprehensive analysis of the relationship between lipid-lowering drugs and sarcoidosis, utilizing Mendelian randomization of drug targ… Show more
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