Genetic and histopathological characterization of Toxoplasma gondii genotypes isolated from free-range chickens reared in the metropolitan region of Rio de Janeiro state, Brazil

Alves, Luciana Casartelli; Pereira, Sandro Antônio; Ferreira, Luíz Cláudio; Couto, Rodrigo de Macedo; Schubach, Tânia Maria Pacheco; Amendoeira, Maria Regina Reis; Silva, Rodrigo da; Langoni, Hélio; Millar, Patricia Riddell; Menezes, Rodrigo Caldas

doi:10.1007/s00436-020-07011-9

Cited by 6 publications

(3 citation statements)

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“…Casartelli-Alves et al [ 36 ] characterized T. gondii strains obtained from free-range chickens reared in the state of Rio de Janeiro, Brazil. Seventeen non-archetypal genotypes were identified among the 36 T .…”

Section: Genotyping Of Non-archetypal Strains Of T Gondiimentioning

confidence: 99%

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Genetic diversity of Toxoplasma gondii in South America: occurrence, immunity, and fate of infection

Brito,

de Lima Bessa,

Bastilho

et al. 2023

Parasites Vectors

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Toxoplasma gondii is an intracellular parasite with a worldwide distribution. Toxoplasma gondii infections are of great concern for public health, and their impact is usually most severe in pregnant women and their foetuses, and in immunocompromised individuals. Displaying considerable genetic diversity, T. gondii strains differ widely according to geographical location, with archetypal strains predominantly found in the Northern Hemisphere and non-archetypal (atypical) strains, with highly diverse genotypes, found mainly in South America. In this review, we present an overview of the identification and distribution of non-archetypal strains of T. gondii. Special attention is paid to the strains that have been isolated in Brazil, their interaction with the host immunological response, and their impact on disease outcomes. The genetic differences among the strains are pivotal to the distinct immunological responses that they elicit. These differences arise from polymorphisms of key proteins released by the parasite, which represent important virulence factors. Infection with divergent non-archetypal strains can lead to unusual manifestations of the disease, even in immunocompetent individuals. Graphical Abstract

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Section: Genotyping Of Non-archetypal Strains Of T Gondiimentioning

confidence: 99%

“…Seventeen non-archetypal genotypes were identified among the 36 T . gondii strains obtained, of which eight had been previously described for different hosts and nine were described for the first time [ 36 ].…”

Section: Genotyping Of Non-archetypal Strains Of T Gondiimentioning

confidence: 99%

Genetic diversity of Toxoplasma gondii in South America: occurrence, immunity, and fate of infection

Brito,

de Lima Bessa,

Bastilho

et al. 2023

Parasites Vectors

View full text Add to dashboard Cite

show abstract

“…Initially, three clonal archetypes, I, II, and III, were recognized, and these seem to prevail in the US and Europe, but in recent years, so-called nonclonal and variant or recombinant genotypes have been found (Grigg et al 2001; Deiró et al 2021). Those nonclonal genotypes are sometimes associated with more severe clinical disease in humans and animals (de-la-Torre et al 2013; Hamilton et al 2019; Pardini et al 2019; Casartelli-Alves et al 2021).…”

Section: Introductionmentioning

confidence: 99%