Genetic analysis of the populations from Northern and Mesopotamian provinces of Argentina by means of 15 autosomal STRs

Inferring Continental Ancestry of Argentineans from Autosomal, Y‐Chromosomal and Mitochondrial DNA

“…Molecular genetics offers suitable tools to investigate bio‐geographic ancestry in detail including the detection and quantification of admixture proportions. Some information has been published about the genetic make‐up of Argentineans either employing markers from autosomal DNA (Sala et al, 1998, 1999; Marino et al, 2006a,b,c; Seldin et al, 2007), from the non‐recombining part of the Y‐chromosome (NRY) (Kayser et al, 1997; Corach et al, 2001; Kayser et al, 2001; Marino et al, 2007), or, to a lesser degree, also from mitochondrial DNA (mtDNA) (Ginther et al, 1993; Corach et al, 1997; Bobillo et al, 2009), but reliable inferences on bio‐geographic ancestry are limited. Also, the combined analysis of uni‐parentally and bi ‐ parentally inherited markers in the same individuals has rarely been done (Martínez Marignac et al, 2004; Corach et al, 2006; Salas et al, 2008).…”

Analysis of locus D9S1120 and its genetic admixture correlation in seven argentina native american ethnic groups

“…Studies performed on erythrocyte genetic systems, GM/KM allotypes (genetic markers of immunoglobulin (Ig) γ and κ chains, respectively), ancestry informative markers, maternal and paternal lineages showed that there are clear differences concerning the ethnic contribution of the selected samples if they were obtained in public or private hospitals, in economically active rural areas, in small isolated tribal groups or in an urban population of randomly selected voluntary donors (Avena et al, ; Martínez Marignac et al, ). The increased frequency of 9RA allele in the Salta province, compared with the other urban populations, could be explained by the fact that significant genetic distances do exist between the Salta Province population and other Argentinean urban populations when autosomal and Y‐chromosome STRs are analyzed (Marino et al, ,; ), suggesting a much higher Native American contribution in the North West of the country (Avena et al, ; Corach et al, ; Marino et al, ).…”

Population stratification in Argentina strongly influences likelihood ratio estimates in paternity testing as revealed by a simulation-based approach

“…The importance of population substructure in Argentina has been minimized in previous studies [20][21][22][23]. More recently, Marino et al [13] measured the impact of population substructure in Argentina, analyzing 15 autosomal STRs in ten population samples from the country, and concluded that no substructure could be detected supporting that a single database of the whole country could be suitable for the correct interpretation of paternity testing and forensic casework results.…”