Abelmoschus esculentus L. Moench, more often known as okra, is a popular and widely consumed vegetable that belongs to the Malvaceae family. It is rich in a variety of essential nutrients, including carbohydrates, proteins, and vitamins. The okra yellow vein mosaic disease (OYVMD) is one of numerous biotic and abiotic variables that pose a danger to okra productivity. In order to investigate the impact of amino acid treatments and algal extracts on inducing systemic resistance in okra against the Okra yellow vein mosaic virus, an experiment was carried out in the fields in the western areas of Samawa City-Muthanna Governorate, Iraq (OYVMV). Research on the impact of the virus found that amino acid and algal extract treatments were most effective, leading to the fewest number of infected okra plants. Peroxidase enzyme, superoxide dismutase, and catalase levels were highest in those who received a combination of amino acids and algal extract. The duration of 14 days was also longer than the spans of 7 and 21 days. While amino acid and algal extract therapy for 21 days had the highest total phenolic concentration, it also had the most negative effects.