Genetic Analysis of Melanoma Types Using Japanese Genomic Database
Hayato Matsumoto,
Hiromi Nagano,
Takayuki Kyutoku
et al.
Abstract:ObjectivesThe purpose of this study is to compare genetic mutations, tumor mutation burden (TMB), and the effects of molecular targeted drugs and immune checkpoint inhibitors (ICIs) in head and neck mucosal melanoma (HNMUM) with those in skin melanoma (SKM) and ocular melanoma (OM).MethodsData were analyzed for 72 consecutive patients with HNMUM, including 366 with SKM and 31 with OM, registered at the Japan National Cancer Center, Center for Cancer Genomics and Advanced Therapeutics (C‐CAT) between June 2019 … Show more
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