Genetic analysis of haplotype data for 23 Y-chromosome short tandem repeat loci in the Turkish population recently settled in Sarajevo, Bosnia and Herzegovina

Abstract

AimTo explore the distribution and polymorphisms of 23 short tandem repeat (STR) loci on the Y chromosome in the Turkish population recently settled in Sarajevo, Bosnia and Herzegovina and to investigate its genetic relationships with the homeland Turkish population and neighboring populations.MethodsThis study included 100 healthy unrelated male individuals from the Turkish population living in Sarajevo. Buccal swab samples were collected as a DNA source. Genomic DNA was extracted using the salting out method and amplification was performed using PowerPlex Y 23 amplification kit. The studied population was compared to other populations using pairwise genetic distances, which were represented with a multi-dimensional scaling plot.ResultsHaplotype and allele frequencies of the sample population were calculated and the results showed that all 100 samples had unique haplotypes. The most polymorphic locus was DYS458, and the least polymorphic DYS391. The observed haplotype diversity was 1.0000 ± 0.0014, with a discrimination capacity of 1.00 and the match probability of 0.01. Rst values showed that our sample population was closely related in both dimensions to the Lebanese and Iraqi populations, while it was more distant from Bosnian, Croatian, and Macedonian populations.ConclusionTurkish population residing in Sarajevo could be observed as a representative Turkish population, since our results were consistent with those previously published for the homeland Turkish population. Also, this study once again proved that geographically close populations were genetically more related to each other.

Contemporary population genetics data for 23 Y-STR loci in the general Bosnian-Herzegovinian population

“…In addition, genetic diversity values for these loci are rather low, ranging from 0.4325 for DYS389I to 0.6206 for DYS391. Similarly, DYS391 locus, with six alleles, was found to be the least polymorphic in the Turkish population recently settled in Sarajevo (Dogan et al, 2014). Conversely, DYS481 is the most polymorphic locus on 480 samples analysed here.…”

Bio-Molecular Allele Frequencies Availability of 23Y-Str Markers Polymorphisms and Odontogenic Diseases in Iraqi Population Study

“…Y-STRs are characterized by male inheritance pattern. (6)(7)(8)(9)(10)(11) Thus, Y-STRs can be used in forensics for the investigation of sexual assault cases, This kit types 23 Y-STR loci in a tested haplotype and includes 6 new Y-STR loci when compared to the previous Y-STR commercial kits, namely DYS576, DYS481, DYS549, DYS533, DYS570, and DYS643 (12,13).…”