Genetic Algorithms to Simplify Infective Endocarditis Outcome

Tuñón, V. Portillo; Gutiérrez, CarlosDueñas; Curiel, Leticia; Baruque, Bruno; Tarragó, Cristina; Corchado, Emilio; Rodríguez, M.A; Ibañez, Alicia Fernández; Lasso, M.; Abad, Sheila Molinero; Morentin, A. Blanco Martinez de; García, A Blanco; González, Juan Francisco Lorenzo

doi:10.1016/s0953-6205(11)60314-2

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“…Traditionally, PVE is classified as early PVE if infection occurs within 12 months from surgery and late PVE if it occurs thereafter [2]. In early PVE, patients are generally infected perioperatively and, more frequently, can present complications involving the sewing ring (abscess, dehiscence, pseudoaneurysms, and fistulae), with Staphylococci, fungi, and Gram-negative bacilli as the main responsible germs [43]. Late PVE generally occurs with valve regurgitation if a bioprosthesis is involved, while mechanical valves may present with large vegetations causing valve stenosis [44].…”

Section: Main Clinical Characteristicsmentioning

confidence: 99%

Multimodality Imaging in the Diagnostic Work-Up of Endocarditis and Cardiac Implantable Electronic Device (CIED) Infection

Galea

Bandera

Lauri

et al. 2020

JCM

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Infective endocarditis (IE) is a serious cardiac condition, which includes a wide range of clinical presentations, with varying degrees of severity. The diagnosis is multifactorial and a proper characterization of disease requires the identification of the primary site of infection (usually the cardiac valve) and the search of secondary systemic complications. Early depiction of local complications or distant embolization has a great impact on patient management and prognosis, as it may induce to aggressive antibiotic treatment or, in more advanced cases, cardiac surgery. In this setting, the multimodality imaging has assumed a pivotal role in the clinical decision making and it requires the physician to be aware of the advantages and disadvantages of each imaging technique. Echocardiography is the first imaging test, but it has several limitations. Therefore, the integration with other imaging modalities (computed tomography, magnetic resonance imaging, nuclear imaging) becomes often necessary. Different strategies should be applied depending on whether the infection is suspected or already ascertained, whether located in native or prosthetic valves, in the left or right chambers, or if it involves an implanted cardiac device. In addition, detection of extracardiac IE-related lesions is crucial for a correct management and treatment. The aim of this review is to illustrate strengths and weaknesses of the various methods in the most common clinical scenarios.

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Section: Main Clinical Characteristicsmentioning

confidence: 99%