Genetic admixture predictors of fetal alcohol spectrum disorders (FASD) in the South African Cape Coloured population
R. Colin Carter,
Zikun Yang,
Tugba Akkaya-Hocagil
et al.
Abstract:Ancestrally admixed populations are underrepresented in genetic studies of complex diseases, which are still dominated by European-descent populations. This is relevant not only from a representation standpoint but also because of admixed populations' unique features, including being enriched for rare variants, for which effect sizes are disproportionately larger than common polymorphisms. Furthermore, results from these populations may be generalizable to other populations. The South African Cape Coloured (SA… Show more
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