1976
DOI: 10.1016/0014-5793(76)80852-6
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Genes and enzymes

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Cited by 3 publications
(2 citation statements)
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“…This means that a change in availability from substrate Sx to substrate Sy can lead to the adaptation of an organism by replacing enzyme Ex by Ey. Such adaptations have been studied experimentally for bacteria (519)(520)(521)(522)(523)(524). Successful examples are the evolution of an acetamidase to a phenylacetamidase (521) and of a ribitol dehydrogenase to a xylitol dehydrogenase (508,522).…”
Section: Protein Differentiationmentioning
confidence: 99%
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“…This means that a change in availability from substrate Sx to substrate Sy can lead to the adaptation of an organism by replacing enzyme Ex by Ey. Such adaptations have been studied experimentally for bacteria (519)(520)(521)(522)(523)(524). Successful examples are the evolution of an acetamidase to a phenylacetamidase (521) and of a ribitol dehydrogenase to a xylitol dehydrogenase (508,522).…”
Section: Protein Differentiationmentioning
confidence: 99%
“…In nature, proteins with new functions are constantly evolving. This is documented by the evolution of heritable resistance to toxic chemicals in insects and to antibiotics in bacteria (519).…”
Section: Protein Differentiationmentioning
confidence: 99%