Generosity and Gender

Vaccine-Induced Tinnitus: A New Consequence of COVID-19

“…Reports of triggering tinnitus in patients who received COVID-19 vaccines have been documented. 4 , 5 Parrino et al in 2021 reported that two out of three patients in their study had no history of audio-vestibular problems before vaccination. 5 Tinnitus was classified as catastrophic in two and as severe in one of them, according to the Tinnitus Handicap Inventory.…”

“…A mixture of people who have received mRNA vaccines (Pfizer/BioNTech and Moderna) and adenovirus-based vaccine (Johnson & Johnson) along with the viral vector vaccine Vaxzevria by Astrazeneca are experiencing the same adverse event of tinnitus. 4 Vaccine Adverse Event Reporting System (VAERS) in the US database also reports of tinnitus among COVID-19 recipients of vaccines from Pfizer-BioNTech and Moderna. Tinnitus has been classified as a “very rare” side effect under the Guidelines for Clinical-Safety Information on Drugs by the Council for International Organizations of Medical Sciences (CIOMS).…”

Selective synthesis of functionalized linear aliphatic primary amines via decarboxylative radical-polar crossover

“…6 In fact, >75% of the top selling drugs of the year 2021–22 contain amine/nitrogen moieties. 7–9 Among different amines, primary amines are highly important due to their wide applications as precursors and valuable intermediates for the synthesis of advanced chemicals, pharmaceuticals, agrochemicals and materials. 3,6 Particularly, linear aliphatic primary amines are vital and every year, at least a million tons are required to meet this demand.…”