Generation of Mature <em>Toxoplasma gondii</em> Bradyzoites in Human Immortalized Myogenic KD3 Cells
Deborah Maus,
Blake Curtis,
David Warschkau
et al.
Abstract:Toxoplasma gondii
is a zoonotic protozoan parasite and one of the most successful foodborne pathogens. Upon infection and dissemination, the parasites convert into the persisting, chronic form called bradyzoites, which reside within cysts in muscle and brain tissue. Despite their importance, bradyzoites remain difficult to investigate directly, owing to limited in vitro models. In addition, the need for new drugs targeting the chronic stage, which is underlined by the lack of eradicating treatment… Show more
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