Generation of human-pig chimeric renal organoids using iPSC technology
Koki Fujimori,
Shuichiro Yamanaka,
Kentaro Shimada
et al.
Abstract:The potential of using porcine organs and human induced pluripotent stem cell (iPSC)-derived organoids as alternative organs for human transplantation has garnered growing attention. However, both approaches still face technological challenges. Interspecies chimeric organ production using human iPSCs is expected to be another promising approach that addresses the challenges associated with organ production. Our research group successfully generated human-mouse chimeric renal organoids by utilizing human iPSC-d… Show more
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