“…16−18 With the continuous research on nanobubbles, diverse methods for nanobubble generation based on four common mechanisms: hydrodynamic, acoustic, particle, and optical, have been proposed and investigated over the past decades, 9 including hydrodynamic cavitation, ultrasonic fragmentation, electrolysis, gas−liquid mixing, external electromagnetic field, porous membranes, temperature gradients, and so on. 19,20 For example, the BNBs prepared by Azevedo et al were produced by dissolving air in water in saturators followed by depressurization/hydrodynamic cavitation of the air-saturated water in a needle valve. 21 Hoon et al used motor-generated mechanical motion for gas−liquid mixing to generate BNBs, which could exist stably for 24 h. 22 Nirmalkar et al used a 20 kHz probe ultrasound processor to induce pressure variations in solutions spiked with sodium dodecyl sulfate, leading to the formation of bubbles.…”