2019
DOI: 10.1038/s41598-019-42042-y
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Generating retinal flow maps from structural optical coherence tomography with artificial intelligence

Abstract: Despite advances in artificial intelligence (AI), its application in medical imaging has been burdened and limited by expert-generated labels. We used images from optical coherence tomography angiography (OCTA), a relatively new imaging modality that measures retinal blood flow, to train an AI algorithm to generate flow maps from standard optical coherence tomography (OCT) images, exceeding the ability and bypassing the need for expert labeling. Deep learning was able to infer flow from single structural OCT i… Show more

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Cited by 75 publications
(66 citation statements)
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“…American scientists [32] propose to use AI in medical imaging more actively and to use images from optical coherent tomography (OCT) to create flow maps from images of standard OCT.…”
Section: B Modern Approaches Using Artificial Intelligence In Identimentioning
confidence: 99%
“…American scientists [32] propose to use AI in medical imaging more actively and to use images from optical coherent tomography (OCT) to create flow maps from images of standard OCT.…”
Section: B Modern Approaches Using Artificial Intelligence In Identimentioning
confidence: 99%
“…32 Recently, transfer learning has also been explored in OCT for detecting choroidal neovascularization, diabetic macular edema, 28 and AMD. 33 In principle, transfer learning can involve a single layer or multiple layers, because each layer has weights that can be retrained. For example, the specific number of layers required for retraining in a 16-layer CNN (Fig.…”
Section: Introductionmentioning
confidence: 99%
“…4 More specifically, deep learning, a subset of machine learning within the field of AI, has been particularly successful in training powerful algorithms for the classification of medical images and other high-dimensional data. [5][6][7][8][9] Taken together, these approaches may offer many benefits for patients, including automated screening and triage of disease and treatment optimization. For example, AIenabled screening of diseases such as diabetic retinopathy, retinopathy of prematurity, and glaucoma could improve early detection and treatment.…”
Section: Introductionmentioning
confidence: 99%