“…Three main components of AIS are negative selection algorithm (NSA), clone selection and immune network model (Igawa & Ohashi, 2009). Application domains of AIS are various and include anomaly and fault detection (Aydin, Karakose, & Akin, 2008;Forrest, Perelson, Allen, & Cherukuri, 1994), classification (Leung, Cheong, & Cheong, 2007), pattern recognition and optimization problems (de Castro & Zuben, 2002).…”