Generalized pitting edema in a patient with dilated cardiomyopathy secondary to hypothyroidism

Matsuura, N.; Saitou, Kenta; Hidaka, Hiroyuki

doi:10.1503/cmaj.220861

Cited by 1 publication

(1 citation statement)

References 11 publications

(21 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the case of drycold type heart failure, cortisol followed by thyroid hormone replacement therapy is considered to be appropriate, in addition to extracellular fluid and inotropic drugs for heart failure. Hormone replacement therapy has been reported to be effective in heart failure with hypothyroidism and adrenocorticism (10,11); however, the pathophysiology and molecular basis of endocrine abnormalities that cause heart failure have not been fully elucidated. Further studies are required to establish solid evidence for the management of patients with hypopituitarism, particularly those with severe disorders.…”

Section: Discussionmentioning

confidence: 99%

Cases: Decompensated Heart Failure Secondary to Hypopituitarism in an Elderly Patient

Yoshino,

Harano,

Shibata

et al. 2024

Intern. Med.

View full text Add to dashboard Cite

Hypopituitarism is difficult to diagnose because of its non-specific symptoms, especially in the presence of comorbidities. A 77-year-old woman with worsening anorexia and exertional dyspnea was initially diagnosed with decompensated dry cold-type heart failure. Hormonal laboratory tests indicated secondary hypothyroidism as a part of the evaluation of heart failure. Furthermore, pituitary magnetic resonance imaging revealed thickening of the pituitary stalk and a loss of signal intensity in the posterior pituitary, thus suggesting lymphocytic hypophysitis. Oral hydrocortisone and levothyroxine improved the persistent anorexia. In this case, hypopituitarism occasionally presented as dry cold-type heart failure, thus making a prompt diagnosis challenging in the setting of concurrent heart failure.

show abstract

Section: Discussionmentioning

confidence: 99%