Generalized molluscum contagiosum in an HIV patient treated with diphencyprone

Chularojanamontri, Leena; Tuchinda, Papapit; Kulthanan, Kanokvalai; Manuskiatti, Woraphong

doi:10.3315/jdcr.2010.1059

Cited by 8 publications

(9 citation statements)

References 9 publications

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“…Diphencyprone is a topical immunomodulator used in multiple skin diseases. Cases of successful treatment with diphencyprone have been reported in immunosuppressed and immunocompetent patients 78,79…”

Section: Treatmentmentioning

confidence: 99%

<p>Molluscum contagiosum: an update and review of new perspectives in etiology, diagnosis, and treatment</p>

Meza‐Romero¹,

Navarrete‐Dechent²,

Downey³

2019

CCID

133

115

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Molluscum contagiosum (MC) is a self-limited infectious dermatosis, frequent in pediatric population, sexually active adults, and immunocompromised individuals. It is caused by molluscum contagiosum virus (MCV) which is a virus of the Poxviridae family. MCV is transmitted mainly by direct contact with infected skin, which can be sexual, non-sexual, or autoinoculation. Clinically, MC presents as firm rounded papules, pink or skin-colored, with a shiny and umbilicated surface. The duration of the lesions is variable, but in most cases, they are self-limited in a period of 6-9 months. The skin lesions may vary in size, shape, and location, which is more frequent in immunosuppressed patients, and could present complications such as eczema and bacterial superinfection. The diagnosis is based on clinical findings. A useful clinical tool is dermoscopy. If the diagnostic doubt persists, confocal microscopy or skin biopsy could be performed. The need for active treatment for MC is controversial; however, there is a consensus that it should be indicated in cases of extensive disease, associated with complications or aesthetic complaints. There are several treatment modalities which include mechanical, chemical, immunomodulatory, and antivirals. The objective of this article is to review the current evidence in etiology, clinical manifestations, diagnosis, and management alternatives of MC.

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Section: Treatmentmentioning

confidence: 99%

<p>Molluscum contagiosum: an update and review of new perspectives in etiology, diagnosis, and treatment</p>

Meza‐Romero¹,

Navarrete‐Dechent²,

Downey³

2019

CCID

133

115

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show abstract

“…Other studies assessing the effect of radiotherapy, diphencyprone, and intralesional interferon alpha were excluded on the basis that these interventions were too risky or prohibitively expensive.…”

Section: Resultsmentioning

confidence: 99%

Interventions for molluscum contagiosum in people infected with human immunodeficiency virus: a systematic review

Martin

2016

Int J Dermatology

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“…[ 7 ] Therapy becomes obligatory, because children may scratch the lesions and infection may spread to other parts or to other people. [ 8 ] Curettage is associated with a high risk of relapse, scarring and most frightening to children if performed repeatedly, owing to pain and fear. [ 9 ]…”

Section: Discussionmentioning

confidence: 99%

Molluscum contagiosum: A novel Ayurvedic approach

Kalasannavar¹,

Sawalgimath

2013

Ancient Sci Life

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SUMMARY:Three cases of molluscum contagiosum (MC) approached our outpatient Department of Dermatology complaining of umbilicated, skin-colored, firm, painless papules over the neck and face. All of them were immune competent. The medical, social, and family history was insignificant. The lesions were, numerous and recurrent. However, MC in healthy people is a self-limiting disease, but it will take about 18 months to resolve by its own. Hence, the treatment becomes necessary to accelerate the healing process, preventing its spread and for cosmetic reasons. Most of the contemporary treatment methods such as cryotherapy, curettage, and topical application of caustic agents are effective but produce local side-effects such as erythema, tenderness, itching, burning sensation, and pain. The present study reports the efficacy of external application of Pratisaraṇīya Kṇāra (the type of Alkali used for smearing over the affected area) and Bilvādi Agada tablet orally in three cases, which yielded encouraging results.

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Generalized molluscum contagiosum in an HIV patient treated with diphencyprone

Cited by 8 publications

References 9 publications

<p>Molluscum contagiosum: an update and review of new perspectives in etiology, diagnosis, and treatment</p>

<p>Molluscum contagiosum: an update and review of new perspectives in etiology, diagnosis, and treatment</p>

Interventions for molluscum contagiosum in people infected with human immunodeficiency virus: a systematic review

Molluscum contagiosum: A novel Ayurvedic approach

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