Generalized granuloma annulare in a patient with type II diabetes mellitus: successful treatment with isotretinoin

Sahin, M Turhan; Türel‐Ermertcan, A; Öztürkcan, Serap; Türkdoğan, Peyker

doi:10.1111/j.1468-3083.2006.01337.x

Cited by 14 publications

(7 citation statements)

References 9 publications

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“…The systemic retinoids isotretinoin 129-136 and etretinate 137,138 have been reported useful in the treatment of generalized GA. Sahin and colleagues 136 reported a case of generalized GA in a diabetic patient successfully treated with isotretinoin (50 mg/d). Their patient had 90% clinical improvement in their lesions.…”

Section: Evaluation and Managementmentioning

confidence: 97%

Granuloma Annulare

Keimig

2015

Dermatologic Clinics

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Granuloma annulare (GA) is a noninfectious granulomatous skin condition that can present with a variety of cutaneous morphologies. It is characterized by collagen degeneration, mucin deposition, and palisaded or interstitial histiocytes. Although the mechanism underlying development of GA is unknown, studies point to a cell-mediated hypersensitivity reaction to an as-yet undetermined antigen. Systemic associations with diabetes, thyroid disorders, lipid abnormalities, malignancy, and infection are described in atypical GA. Treatment is divided into localized skin-directed therapies and systemic immunomodulatory or immunosuppressive therapies. The selected treatment modality should be based on disease severity, comorbid conditions, consideration of potential side effects, and patient preference.

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Section: Evaluation and Managementmentioning

confidence: 97%

Granuloma Annulare

Keimig

2015

Dermatologic Clinics

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“…Granuloma annulare (GA) presents as erythematous to flesh-colored papules coalescing to form an oval or ring lesion. GA often presents asymptomatically but can cause pruritus or a burning sensation ( 54 ). The association between granuloma annulare and diabetes is controversial.…”

Section: Other Diabetes-related Conditionsmentioning

confidence: 99%

Cutaneous Manifestations of Diabetes Mellitus

et al. 2015

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“…GA often presents asymptomatically but can cause pruritus or a burning sensation (54). The association between granuloma annulare and diabetes is controversial.…”

Section: Granuloma Annularementioning

confidence: 99%