Generalized fixed drug eruption mimicking CD8+ cutaneous T‐cell lymphoma in HIV

Jacobsen, Emilie; Tarabadkar, Erica S.; Shinohara, Michi M.

doi:10.1111/cup.13376

Cited by 4 publications

(2 citation statements)

References 13 publications

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“…Rare cases of acute generalized exanthematous pustulosis or linear folliculotropic eruption have been documented [148,149]. Generalized fixed drug eruption with features of CD8-positive T-cell lymphoma has also been documented [150]. Drug-induced pseudolymphomas that mimic CTCL present as solitary or generalized erythematous patches, plaques, or nodules, or morbilliform eruptions, most commonly correlated with anticonvulsant therapy [151].…”

Section: Clinical Presentationmentioning

confidence: 99%

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Drug Reactions

Fung¹,

Tartar²,

Brassard³

2020

Hospital-Based Dermatopathology

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Section: Clinical Presentationmentioning

confidence: 99%

“…A wide variety of clinical presentations have been reported, including AGEP, linear folliculotropic lesions, red tattoo reactions (Fig. 15.19), and generalized fixed drug eruption [148][149][150].…”

Section: Differential Diagnosismentioning

confidence: 99%

Drug Reactions

Fung¹,

Tartar²,

Brassard³

2020

Hospital-Based Dermatopathology

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HIV and the Skin

Bunker,

Piguet

2024

Rook's Textbook of Dermatology

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Within 2 years of defining acquired immune deficiency syndrome (AIDS) as a distinctive syndrome in 1981, human immunodeficiency virus (HIV) was identified as the causative agent. Dermatological involvement in AIDS has been appreciated since the disease was first recognised. Mucocutaneous involvement establishes criteria for diagnosis and staging; the prognostic significance of some complications, for example pruritic papular eruption/eosinophilic folliculitis, hairy leukoplakia and Kaposi sarcoma (KS), was well recognised before specific treatments were introduced. The proportion of patients with skin complications and the number of these manifestations in any one patient increase as HIV infection progresses and AIDS develops. The incidence and severity of several common cutaneous diseases (such as mollusca, herpes simplex and seborrhoeic dermatitis) are increased in patients with HIV and this correlates in many instances with the absolute numbers of CD4+ T cells. The effect HIV infection may have on some dermatological conditions such as psoriasis and leprosy is less clear‐cut. The advent of highly active combined antiretroviral therapy (ART) has been incalculably beneficial to patients with HIV, but novel side effects of these drugs (such as lipodystrophy) have emerged, and the skin can be affected by manifestations of the immune reconstitution inflammatory syndrome/immune reconstitution associated disease. The dermatological complications of HIV and AIDS may be distressing to patients and difficult for dermatologists to diagnose and manage. Also, many dermatoses presenting in the population at large need to be regarded as ‘indicator conditions’ to prompt advice about, and initiation of, HIV testing.

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Hydrocodone/paracetamol/ibuprofen

2019

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Generalized fixed drug eruption mimicking CD8+ cutaneous T‐cell lymphoma in HIV

Cited by 4 publications

References 13 publications

Drug Reactions

Drug Reactions

HIV and the Skin

Hydrocodone/paracetamol/ibuprofen

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