Generalized eruptive syringomas

Jamalipour, Mahnaz; Heidarpour, Mitra; Rajabi, Parvin

doi:10.4103/0019-5154.48992

Cited by 25 publications

(21 citation statements)

References 9 publications

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“…[1] Occasionally, however, generalized eruptive syringoma develops in a more widespread distribution. [7] Other rare clinical forms include unilateral linear,[8] lichen planus-like, alopecia,[9] or milium-like syringoma. [10]…”

Section: Discussionmentioning

confidence: 99%

Cutaneous syringoma: A clinicopathologic study of 34 new cases and review of the literature

Ghanadan

Khosravi

2013

Indian J Dermatol

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Background:Syringoma is a benign adnexal tumor derived from intraepidermal eccrine duct.Aim:The aim of the study is to report the experience concerning syringoma by reviewing the clinical and histopathologic features of a series of 34 histologically diagnosed syringoma patients observed over a period of six years.Materials and Methods:Thirty-four patients were sorted into two groups, localized and generalized syringoma, according to the Friedman and Butler classification. Different histopathologic findings were recorded in specially designed questionnaires for further analysis.Results:Ninety-seven percent of the patients were females with the mean age of 27.6 years. The mean duration of the lesions before the presentations was six years. The diagnosis of syringoma was only considered in 23 patients (67.6%) and was the initial diagnosis in only 13 (38.2%) patients. All histological findings were seen more common in our cases. in comparison to the documented cases in the literature. Clear cell change of epithelial eccrine cells was 85.2% and there was no difference in the histopathological findings in the two groups. Our patients with generalized syringoma (GS) had a considerable lower age of onset than the ones with localized syringoma (LS) (P = 0.027).Conclusion:Our patients with generalized syringoma were younger than the ones with localized syringoma. Distribution of the generalized syringoma was mainly in the chest and neck followed by the forearms whereas localized syringoma was mostly confined to the face, axilla and genitalia. There were also some conditions associated with our cases including sarcoidosis, calcinosis cutis and basal cell carcinoma.

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Section: Discussionmentioning

confidence: 99%

Cutaneous syringoma: A clinicopathologic study of 34 new cases and review of the literature

Ghanadan

Khosravi

2013

Indian J Dermatol

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“…Syringomas usually involve face, neck, and trunk with a female predominance [1, 2]. However, vulvar syringoma without extragenital involvement is an extremely rare variant of syringoma [1].…”

Section: Introductionmentioning

confidence: 99%

Vulvar Nonclear Cell Syringoma Associated with Pruritus and Diabetes Mellitus

Akoğlu

İbiloğlu

Durmazlar

2013

Case Reports in Dermatological Medicine

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Background. Syringoma is a benign eccrine sweat gland tumor, characterized by multiple skin colored or slightly yellowish papules. Vulvar syringoma without extragenital involvement is an extremely rare variant of syringoma. Mail Observations. Herein, we report a 40-year-old diabetic female patient who presented with only lichenified plaques on the vulvar region without any extragenital lesions. Diagnosis of vulvar syringoma was made depending on the characteristic double lined cystic enlargements and comma-like tails found in histopathological examination. Immunohistochemical stains for estrogen and progesterone receptors were negative. Conclusion. Vulvar syringoma may present with no obvious papules on lichenified plaques.

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“…Generalize eruptif form ise vücudun farklı bölgelerinde kısa sürede ortaya çıkan çok sayıda siringomun bulunduğu oldukça nadir görülen bir klinik tiptir (2). Klinik, histolojik ve histokimyasal özellikleri klasik siringomdan farklı olmayan erüptif siringom (4) ilk olarak Darier ve Jaquet tarafından 1887'de tanımlanmıştır (3,5). Lezyonlar genellikle puberte öncesinde veya puberte boyunca ortaya çıkar (3,4).…”

Section: Discussionunclassified

Section: Introductionunclassified

“…Siringom kadınlarda daha sık görülen ekrin ter bezi kanallarından kaynaklanan iyi huylu bir tümördür (1)(2)(3)(4)(5). Lezyonlar en sık yüzde, özellikle periorbital bölgede yerleşmiş olup, deri renginde veya sarımsı olabilen, birkaç milimetre çaplarında papüller ile karakterizedir (2,3). Oldukça nadir bir klinik varyant olan generalize eruptif formun tipik lezyonları gövde ön yüz, boyun, üst ekstremite fleksörleri, aksillalar, omuzlar ve karında yaygın olarak bulunan, deri renginde, sarımsı veya hafif hiperpigmente olabilen, 3-5 mm çapında papüllerdir (2)(3)(4)(5).…”

Section: Introductionunclassified

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Generalized Eruptive Syringoma

Aktürk¹,

Öztürk²,

Öztürk³

et al. 2011

Turk J Dermatol

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Siringom ekrin ter bezi kanallarından kaynaklanan ve kadınlarda daha sık görülen iyi huylu bir deri eki tümörüdür. Genellikle periorbital bölgeye yerleşen deri renginde veya sarımsı renkte küçük papüllerle karakterizedir. Generalize eruptif siringom ise lezyonların vücutta yaygın olarak bulunduğu siringomun nadir görülen bir klinik şeklidir. Peripubertal dönemde ortaya çıkmaya başlayan lezyonlar kendiliğinden gerileyebilir. Gerilemeyen olgularda topikal tretinoin veya adapalene, eksizyon, elektrokoagülasyon, kriyoterapi, karbondioksit (CO 2) lazer gibi tedavi yöntemleri denenebilir. Burada, periorbital bölge, gövde ve kolların üst kısımlarında simetrik dağılan, çok sayıda deri renginde-sarımsı papülleri bulunan, peripubertal dönemde başlayan ve generalize erüptif siringom olarak tanı konulan yirmi dört yaşında bir bayan hasta sunulmaktadır.

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Generalized eruptive syringomas

Cited by 25 publications

References 9 publications

Cutaneous syringoma: A clinicopathologic study of 34 new cases and review of the literature

Cutaneous syringoma: A clinicopathologic study of 34 new cases and review of the literature

Vulvar Nonclear Cell Syringoma Associated with Pruritus and Diabetes Mellitus

Generalized Eruptive Syringoma

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