Generalised idiopathic benign acanthosis nigricans with onset during infancy: report of two patients

Abstract

<p>Generalised acanthosis nigricans (AN) is usually seen in association with insulin resistance or internal malignancy in adults. Very rarely, this may occur in children without any evidence of systemic disease and runs a benign course. Its management requires only watchful waiting. Here, we report two children with benign AN who had onset of AN during infancy and showed spontaneous improvement during follow up for a mean duration of 7.7±0.14 years.</p>