General Use of Chinese Herbal Products among Female Patients with Mastitis in Taiwan

Chou, Shu-Huey; Huang, Chun Che; Lin, Ching‐Heng; Wu, Kun-Chang; Chiang, Pei-Jung

doi:10.1155/2022/3876240

Cited by 2 publications

(1 citation statement)

References 28 publications

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“…These herbs have been commonly prescribed to support lactation in TCM. Wang Bu Liu Xing is traditionally used for promoting lactation and treating breast abscess (45), while Lu Lu Tong has been linked with improving circulation and reducing swelling (46). Our study further revealed that among dual combinations of CHP, the pairing of Wang Bu Liu Xing and Lu Lu Tong was the most common.…”

Section: Discussionmentioning

confidence: 51%

Advancing breastfeeding promotion: leveraging integrative natural galactagogues and unveiling their potential roles—Insights from a 19-year Taiwan nationwide registry to address lactation insufficiency in postpartum women

Liao,

Chien,

Hsu

et al. 2024

Front. Nutr.

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BackgroundLactation insufficiency is a prevalent challenge for nursing mothers globally. There is a growing interest in the use of herbal galactagogues for enhancing lactation, but their therapeutic efficacy and underlying mechanisms need thorough investigation. This study aims to investigate the efficacy and mechanisms of action of herbal galactagogues in addressing lactation insufficiency by utilizing real-world data and employing a network analysis approach.MethodsOur retrospective study used Taiwan’s Longitudinal Health Insurance Database 2000 (LHID2000) to identify 490 patients diagnosed with lactation insufficiency from 2000 to 2018. We analyzed demographic characteristics, co-existing diseases, and prescription patterns for both users and non-users of Chinese herbal products (CHP). Additionally, we utilized a network analysis approach to explore potential compounds and targets in the most frequently used CHP, the Wang Bu Liu Xing and Lu Lu Tong herb pair (WLHP) combination.ResultsOut of 490 patients, 81% were CHP users. There were no significant differences in demographic characteristics between CHP users and non-users, but we observed a notable divergence in the prevalence of co-existing diseases. A detailed examination of CHP prescriptions revealed the predominance of WLHP, prompting further investigation. Comprehensive analysis identified 29 major compounds in WLHP, which were associated with 215 unique targets. Intersection analysis revealed 101 overlapping targets between WLHP and lactation, suggesting their potential as therapeutic targets for lactation insufficiency treatment. Topological analysis of the protein-protein interaction (PPI) network identified 13 hub genes potentially crucial for the therapeutic effect of WLHP. Functional enrichment analysis showed that these targets were involved in critical lactation regulation pathways, including the PI3K-Akt signaling pathway, prolactin signaling pathway, estrogen signaling pathway, and AMPK signaling pathway.DiscussionThis study emphasizes the potential of CHP, specifically the WLHP combination, in managing lactation insufficiency. The multi-compound, multi-target approach of WLHP and its interaction with key biological processes and signaling pathways offer valuable insights into the underlying mechanisms of its therapeutic effects. These findings warrant further experimental validation and can guide future research and clinical applications of CHP in lactation insufficiency treatment.

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Section: Discussionmentioning

confidence: 51%

Advancing breastfeeding promotion: leveraging integrative natural galactagogues and unveiling their potential roles—Insights from a 19-year Taiwan nationwide registry to address lactation insufficiency in postpartum women

Liao,

Chien,

Hsu

et al. 2024

Front. Nutr.

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Effect of nursing teaching protocol on mastitis prognosis: quasi-experimental research design

Hashem,

Ahmed,

Elnga Ahmed

et al. 2023

Egyptian Nursing Journal

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Background Mastitis is a problematic issue because it may lead to many complications as early termination of breastfeeding, formation of breast abscess, deformity of breast tissue, and recurrence. Nursing management is conducted to deepen patients’ understanding of the diseases, enhancing self-care ability, and establishing healthy living habits. Aim The aim of this study is to evaluate the effect of a nursing teaching protocol on mastitis prognosis. Design A quasi-experimental research design was utilized. Setting The study was conducted in the breast unit in general surgery department at Main Assiut University Hospital. Sample A convenient sample of sixty adult female patients diagnosed with mastitis was included. Toolss Four tools used I: An interview questionnaire sheet, II: Mastitis self-care practices, III: Numeric Pain Rating Scale, and IV: Mastitis prognosis sheet. Results The mean age of both study and control groups was (37.57±9.01, 38.30±9.24 respectively). (60.0% and 50.0% respectively) of both groups had lactational mastitis. There was statistically significant improvement in study group’s level of knowledge and self-care practices at follow up. Moreover, (63.3%, 70.0% respectively) of both groups had severe pain at base line. However, at follow up (66.7%,) of study group didn’t have any pain and cured completely. while (40.0%) of control still having severe pain, (33.3%) discontinued breast feeding and (20.0%) converted into breast abscess. Conclusion Implementation of a nursing teaching protocol had a positive outcome on mastitis prognosis. Recommendation Distribution of a mastitis teaching protocol for patients with mastitis to improve prognosis.

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General Use of Chinese Herbal Products among Female Patients with Mastitis in Taiwan

Cited by 2 publications

References 28 publications

Advancing breastfeeding promotion: leveraging integrative natural galactagogues and unveiling their potential roles—Insights from a 19-year Taiwan nationwide registry to address lactation insufficiency in postpartum women

Advancing breastfeeding promotion: leveraging integrative natural galactagogues and unveiling their potential roles—Insights from a 19-year Taiwan nationwide registry to address lactation insufficiency in postpartum women

Effect of nursing teaching protocol on mastitis prognosis: quasi-experimental research design

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