Over the past two decades, substantial efforts have been made to understand
the way in which physics enforces the ordinary topology and causal structure
that we observe, from subnuclear to cosmological scales. We review the status
of topological censorship and the topology of event horizons; chronology
protection in classical and semiclassical gravity; and related progress in
establishing quantum energy inequalities.Comment: Dedicated to Rafael Sorkin, whose tutoring and friendship from third
grade on is responsible for one of us (JF) having spent his adult life in
physics and whose work has inspired both of us. In v.2, some references are
updated, and references are added to early work on 2+1 spacetimes and to work
on event-horizon topolog