General Movements in Very Preterm Children and Neurodevelopment at 2 and 4 Years

Spittle, Alicia J; Spencer‐Smith, Megan; Cheong, Jeanie L.Y.; Eeles, Abbey L; Lee, Katherine J.; Anderson, Peter J.; Doyle, Lex W.

doi:10.1542/peds.2013-0177

Cited by 109 publications

(155 citation statements)

References 24 publications

Supporting

Mentioning

143

Contrasting

Order By: Relevance

“…General Movement Assessment in preterm infants has been shown to be an effective predictor of cerebral palsy. [25][26][27] However, because only 1 infant in our cohort had cerebral palsy, we focused on determining the ability of the General Movement Assessment to predict abnormal motor performance. Notably, we found aberrant FM to be significantly and separately associated with each of the abnormal motor, language, and cognitive outcomes.…”

Section: Discussionmentioning

confidence: 99%

White Matter Injury and General Movements in High-Risk Preterm Infants

Peyton¹,

Yang

Msall

et al. 2016

AJNR Am J Neuroradiol

View full text Add to dashboard Cite

BACKGROUND AND PURPOSE:Very preterm infants (birth weight, Ͻ1500 g) are at increased risk of cognitive and motor impairment, including cerebral palsy. These adverse neurodevelopmental outcomes are associated with white matter abnormalities on MR imaging at term-equivalent age. Cerebral palsy has been predicted by analysis of spontaneous movements in the infant termed "General Movement Assessment." The goal of this study was to determine the utility of General Movement Assessment in predicting adverse cognitive, language, and motor outcomes in very preterm infants and to identify brain imaging markers associated with both adverse outcomes and aberrant general movements.

show abstract

Section: Discussionmentioning

confidence: 99%

White Matter Injury and General Movements in High-Risk Preterm Infants

Peyton¹,

Yang

Msall

et al. 2016

AJNR Am J Neuroradiol

View full text Add to dashboard Cite

show abstract

“…However, similar to other studies, the specificity of the GMA was lower than the sensitivity. 8,19 While GMA at 3 months corrected age has higher specificity, 20,21 an earlier GMA before hospital discharge may help expedite referrals to follow-up intervention services, rather than delaying access to intervention until GMA post-term. The low specificity does mean, however, that children may be referred to early intervention that might prove to be unnecessary.…”

Section: Discussionmentioning

confidence: 99%

“…20,21 Previous studies of GMA in the first few weeks after birth, 8,18 and GMA at 36 weeks postmenstrual age, 22 reported dichotomized normal/abnormal outcome according to a neurological assessment, and CP diagnosis. Our study shows that early GMA may also be related to gross and fine motor development, with associations noted between abnormal GMA at preterm and TEA time points and worse motor scores.…”

Section: Discussionmentioning

confidence: 99%

“…15 It assesses neurodevelopment across gross motor, fine motor, neurological, postural, and sensory domains, with functional grades for each domain summed for a total functional grade score categorized as normal (score 6-8), minimal deviation (score 9-11), mild deviation (12-13), moderate deviation (14)(15)(16)(17)(18)(19), severe (20)(21)(22)(23)(24)(25), and profound (>25).…”

Section: Nsmdamentioning

confidence: 99%

See 1 more Smart Citation

Preterm and term‐equivalent age general movements and 1‐year neurodevelopmental outcomes for infants born before 30 weeks' gestation

Olsen

Allinson

Doyle

et al. 2017

Develop Med Child Neuro

View full text Add to dashboard Cite

Aim To examine the associations between Prechtl's General Movements Assessment (GMA), conducted from birth to term‐equivalent age, and neurodevelopmental outcomes at 12 months corrected age, in infants born very preterm. Method One hundred and thirty‐seven infants born before 30 weeks' gestation had serial GMA (categorized as ‘normal’ or ‘abnormal’) before term and at term‐equivalent age. At 12 months corrected age, neurodevelopment was assessed using the Alberta Infant Motor Scale (AIMS); Neurological, Sensory, Motor, Developmental Assessment (NSMDA); and Touwen Infant Neurological Examination (TINE). The relationships between GMA at four time points and 12‐month neurodevelopmental assessments were examined using regression models. Results Abnormal GMA at all time points were associated with worse continuous scores on the AIMS, NSMDA, and TINE (p<0.05). Abnormal GMA before term and at term‐equivalent age were associated with increased odds of mild–severe dysfunction on the NSMDA (odds ratio [OR] 4.26, 95% confidence interval [CI] 1.55–11.71, p<0.01; and OR 4.16, 95% CI 1.55–11.17, p<0.01 respectively) and abnormal GMA before term with increased odds of suboptimal–abnormal motor function on the TINE (OR 2.75, 95% CI 1.10–6.85, p=0.03). Interpretation Abnormal GMA before term and at term‐equivalent age were associated with worse neurodevelopment at 12 months corrected age in children born very preterm. What this paper adds Abnormal general movements before term predict developmental deficits at 1 year in infants born very preterm. General Movements Assessment before term identifies at‐risk infants born very preterm.

show abstract

“…The general movements assessment has been shown to be a sensitive and non-intrusive means of predicting impairments, with an abnormal general movements at three months associated with worse motor and cognitive outcomes at two and four years of age amongst children born very preterm (Spittle et al, 2013). It has been suggested that the general movements assessment may predict cognitive function in children born very preterm at seven to 11 years of age as well (Bruggink et al, 2010).…”

Section: Connection Between Cognitive and Motor Development In Childrmentioning

confidence: 99%

Physiotherapy intervention for 4-5 year old children born extremely preterm and/or extremely low birth weight

Brown¹

View full text Add to dashboard Cite

Neurodevelopmental impairments amongst the extremely low birth weight (ELBW) or extremely preterm population are well recognised. However, support services for these children who have mild impairments are lacking. This research aimed to explore the performance of a group of non-disabled ELBW or extremely preterm children with minimal/mild impairments over a 12 month period at a critical time-point, coinciding with the commencement of formal education. Performance of these children was established, as well as whether impairments persist. Persistence of impairments may suggest a widening gap between performance of these children and expected performance of term born peers. Additionally, this research aimed to investigate the short term and longer term impact of group-based physiotherapy intervention compared to standard care. SubjectsFifty children born ELBW and/or extremely preterm (26 males; mean birth weight: 838.8g, SD 174.8g; mean gestational age: 27.0 weeks, SD 2.0 weeks) with minimal/mild motor impairments and a mean age (corrected for prematurity) of 50 months (SD 2.6 months) at baseline. Twenty-four children were randomised to intervention and 26 children to standard care. MethodsChildren were assessed by paediatric physiotherapists blinded to group allocation. A set testing protocol was used. Baseline assessment included: Movement Assessment Battery for Children second-edition (MABC-2), tests of postural stability and limb strength, Child Behavior Checklist (CBCL) and Beery Visual-Motor Integration Test 5 th Edition (Beery VMI). Following baseline assessment, children were randomly allocated to intervention or standard care. All children were assessed on motor and postural tests at the conclusion of the intervention. Goal Attainment Scaling (GAS) was utilised within the intervention group. At one year post baseline assessment, all children were assessed on baseline tests, as well as Peabody Picture Vocabulary Test 4 th Edition (PPVT-4). The group had low average motor co-ordination, lower than expected postural stability and strength, and acceptable behaviour. Mean percentile rank on MABC-2 was 31%.However, 30% of children had a score less than or equal to the 15 th percentile, indicating at risk of or having a definite motor problem and these children had poorer postural outcomes compared to children with normal motor performance. Behaviour was within normal range according to performance on CBCL, although between 11-15% of children had a score within the clinical range. Behaviour of males was poorer than that of females. Study IV: GAS to explore effect of group-based physiotherapy intervention on personal growth of non-disabled ELBW children Intervention was effective with GAS mean T score of the group exceeding the expected level (mean=58.17, SD=0.82). Goal attainment was associated with motor co-ordination 4 and children with better motor skills post intervention, were more successful in reaching goals. Females improved more than males on GAS. Study V: Behaviour of 4-5 year old non-disabled E...

show abstract

General Movements in Very Preterm Children and Neurodevelopment at 2 and 4 Years

Cited by 109 publications

References 24 publications

White Matter Injury and General Movements in High-Risk Preterm Infants

White Matter Injury and General Movements in High-Risk Preterm Infants

Preterm and term‐equivalent age general movements and 1‐year neurodevelopmental outcomes for infants born before 30 weeks' gestation

Physiotherapy intervention for 4-5 year old children born extremely preterm and/or extremely low birth weight

Contact Info

Product

Resources

About