1950
DOI: 10.1097/00000658-195009000-00018
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General Hypothermia for Experimental Intracardiac Surgery

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Cited by 390 publications
(52 citation statements)
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“…1 Over the last 10 years, the medical community has witnessed a resurgence of interest in the use of moderate hypothermia (30-33…”
Section: Introductionmentioning
confidence: 99%
“…1 Over the last 10 years, the medical community has witnessed a resurgence of interest in the use of moderate hypothermia (30-33…”
Section: Introductionmentioning
confidence: 99%
“…Den entscheidenden Anstoß zur sichtkontrollierten Chirurgie am eröffneten Herzen, die eine operative Korrektur intrakardialer Herzfehler möglich machte, lieferten die tierexperimentellen Arbeiten zum Kreislaufstillstand in Oberflä-chenhypothermie von Bigelow in Toronto (1950, [4]) und deren klinische Umsetzung von Lewis u. Taufic in Minneapolis (1952, [5]) und Swan in Denver (1953, [6]) sowie die Arbeiten zur extrakorporalen Zirkulation unter Einsatz erster HerzLungen-Maschinen von Gibbon in Philadelphia (1953, [7]). Trotz der Widrigkeiten der Nachkriegszeit gelang es einer ganzen Generation mutiger Chirurgen in Deutschland, sich an diesen Entwicklungen zu beteiligen und die offene Herzchirurgie nachhaltig mitzugestalten [8].…”
Section: Geburt Der Chirurgie Am Offenen Herzenunclassified
“…114 Wilfred Bigelow first showed that blood flow could be entirely arrested in cooled animals without deleterious effects. 115 This discovery allowed procedures to be performed on a stopped heart in a blood-free environment, which made modern cardiac surgery possible. In fact, using a technique devised by Charles Drew in which patients were cooled to 15°C, Ronald Belsey performed human cardiac surgery without any circulation for Ͼ60 minutes (the perfusionist would step out of the operating room) without deleterious cerebral consequences.…”
Section: Therapeutic Hypothermiamentioning
confidence: 99%