General evaluation of periventricular-intraventricular hemorrhage in premature infants in mainland China

Liu, Jing; Chang, Li-Wen; Wang, Qi; Qin, Gui-lian

doi:10.5152/jtgga.2010.02

Cited by 4 publications

(1 citation statement)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Asphyxia is related to abnormal gas exchange which results in oxygen deficit and hypercapnea. In a study by Liu et al [ 17 ] on 1122 infants born before week 37 of gestational age, asphyxia is mentioned as one of major risk factors for IVH. Severe asphyxia, defined as Apgar score of ≤3 at 1 and 5 min, is also listed as an IVH risk factor in infants with birth weight <1500 g (Adegoke et al) [ 18 ].…”

Section: Discussionmentioning

confidence: 99%

Intraventricular hemorrhage in neonates born before 32 weeks of gestation—retrospective analysis of risk factors

et al. 2016

View full text Add to dashboard Cite

IntroductionIntraventricular hemorrhage (IVH) affects 15–20 % of babies born before 32 weeks of pregnancy. A lot of risk factors of developing IVH are known. The making appropriate recommendations for dealing with infant born less than 32 weeks of gestation aimed at reducing the incidence of IVH is still needed. The study aim was to determine the incidence and analyze risk factors of IVH stage 3 and 4 in infants born before 32 + 0 weeks of pregnancy.MethodsThe retrospective analysis of 267 preterm babies (24 to 32 weeks of gestation) hospitalized in 2011–2013 at Department of Neonatology, Poznan University of Medical Sciences was performed. The diagnosis of IVH was confirmed by ultrasound scans according to Papille criteria. Stage 3 and 4 of IVH was confirmed in 14 (25 %) newborns from 23 to 24 weeks of gestation; 21 (37.5 %) from 25 to 26 weeks of gestation; 11 (19.6 %) from 27 to 28 weeks of gestation; 9 (16.1 %) from 29 to 30 weeks of gestation; and 1 (1.8 %) from 31 to 32 weeks of gestation.ResultThe incidence of IVH stage 3 and 4 was higher in children: with less use of AST (OR 1.27; 0.62–2.61), born out of third-level hospitals (OR 2.25; 1.23–4.08), born with asphyxia (OR 3.46; 1.8–6.64), with acidosis treated with NaHCO3 (OR 6.67; 3.78–11.75), those who in the first days of life were treated for hypotension (OR 9.92; 5.12–19.21).ConclusionNo or uncompleted antenatal steroid therapy increased probability for development of severe intraventricular hemorrhage. Antenatal steroids therapy should be promoted among women at risk of a premature delivery. Hypotension therapy with catecholamines and acidosis with sodium hydrogen carbonate should be carefully considered. The use of appropriate prophylaxis of perinatal (antenatal steroids therapy women at risk of preterm birth, limiting the indications for the use of catecholamines for hypotension treatment and sodium hydrogen carbonate for acidosis therapy, limitation of preterm deliveries outside tertiary referral centeres) significantly reduces the incidence of intraventricular hemorrhage stage 3 and 4. The significance of intraventricular hemorrhage creates a need to carry out periodical analysis, at regional level, concerning its incidence, causes and effects to improve local treatment outcomes by identifying further courses of action.

show abstract

Section: Discussionmentioning

confidence: 99%

Intraventricular hemorrhage in neonates born before 32 weeks of gestation—retrospective analysis of risk factors

et al. 2016

View full text Add to dashboard Cite

show abstract

Next‐generation sequencing to investigate circular RNA profiles in the peripheral blood of preterm neonates with bronchopulmonary dysplasia

Mao

Guo

Qiu

et al. 2020

Clinical Laboratory Analysis

View full text Add to dashboard Cite

Background Circular RNAs (circRNAs) are emerging noncoding RNAs that are involved in many biological processes and diseases. The expression profile of circRNAs in preterm neonates with bronchopulmonary dysplasia (BPD) remains unresolved. Methods In BPD infants, peripheral venous blood was drawn and circRNAs were extracted and sequenced by next‐generation sequencing. The levels of the selected circRNAs were measured by real‐time quantitative reverse transcription PCR. Results Among thousands of circRNAs, 491 circRNAs were significantly changed. Among the top 10 changed circRNAs, hsa_circ_0003122, hsa_circ_0003357, hsa_circ_0009983, hsa_circ_0003037, and hsa_circ_0009256 were significantly increased, while hsa_circ_0014932, hsa_circ_0015109, hsa_circ_0017811, hsa_circ_0020588, and hsa_circ_0015066 were significantly decreased. These altered circRNAs are involved in complicated biological functions and signaling pathways. Additionally, hsa_circ_0005577 (hsa_circ_FANCL), which was significantly increased in the moderate‐to‐severe BPD subjects, was correlated with oxygenation therapy. Conclusion These results suggest that an aberrant circRNA profile in the peripheral blood of BPD infants might be important in BPD pathogenesis.

show abstract

Physiological response of premature infants due to the administration of pseudostem banana nest innovation to the incubator

Hapsari

Widyawati

Suryono

2019

J. Phys.: Conf. Ser.

View full text Add to dashboard Cite

In this study, innovation of banana pseudostem nest was conducted to assess the physiological response of premature infants due to the provision of pseudostem banana nest innovation in the incubator. This innovation is needed because premature babies need conditions that promote physiological response functions to increase body temperature, gain weight and assess changes in oxygen saturation. Unfortunately, so far there is no temperature stabilizer in the incubator, the incubator is made of electric and heating elements only so that some physical parameters cannot be accommodated with the incubator. Therefore, this paper proposes the innovation of pseudostem banana nest because it has a 400% water absorption level, a higher temperature stabilization on the fibers in commonly used materials. This study measures physiological responses. The research procedure begins with the manufacture of dried banana pseudostem ingredients, making pseudostem banana nest from banana midribs and coated with a cloth shaped like a hand containment. This research uses a quasi-experimental design method with pre-post test control group design. The sampling technique used was nonprobability sampling by consecutive sampling. A sample of 30 preterm infants was divided into 15 control group samples, 15 intervention group samples. Action procedure, the researcher treated the intervention group by placing nest pseudostem banana in the incubator until it surrounded the premature baby for three consecutive days. Measurements were made on parameters of body temperature, weight, oxygen saturation before and after intervention in the control group and intervention group for three consecutive days. The results of this study were obtained significant differences in body temperature, oxygen saturation before and after given nest pseudostem banana with a p-value of 0.001; 0.003. In this study, there were no significant differences in body weight before and after being given nest pseudostem banana with a p-value of 0.837.

show abstract

General evaluation of periventricular-intraventricular hemorrhage in premature infants in mainland China

Cited by 4 publications

References 14 publications

Intraventricular hemorrhage in neonates born before 32 weeks of gestation—retrospective analysis of risk factors

Intraventricular hemorrhage in neonates born before 32 weeks of gestation—retrospective analysis of risk factors

Next‐generation sequencing to investigate circular RNA profiles in the peripheral blood of preterm neonates with bronchopulmonary dysplasia

Physiological response of premature infants due to the administration of pseudostem banana nest innovation to the incubator

Contact Info

Product

Resources

About