General and disease-specific quality of life in patients with chronic suppurative otitis media - a prospective study

Baumann, Ingo; Gerendas, Bianca S.; Plinkert, Peter K.; Praetorius, Mark

doi:10.1186/1477-7525-9-48

Cited by 88 publications

(94 citation statements)

References 17 publications

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“…About 65-330 million people suffer from ear infection worldwide and 60% of them have significant hearing impairment [1]. If left untreated long term consequences of persistent severe ear infection can arise including speech disorder, hearing loss and lower overall quality of life [2,3]. Many studies have reported high level of resistance pattern to different antibiotics from bacterial isolates from ear infections [4,5].…”

Section: Introductionmentioning

confidence: 99%

In Vitro Evaluation of Ethanolic and Aqueous Crude Extracts of Newbouldia laevis Leaves on Bacterial Isolates from Ear Infections

Kanu

Kalu

2018

IJPPE

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Abstract. The antibacterial effects of ethanolic and aqueous crude extract of leaves of Newbouldia laevis were evaluated against pathogenic Staphylococcus aureus, Staphylococcus epidermidis, Bacillus spp, Pseudomonas aeruginosa and Escherichia coli isolated from ear infections. A concentration gradient of the ethanolic and aqueous extract (12.5 mg/ml -100 mg/ml) was prepared and its effectiveness was tested by agar well diffusion method and nutrient broth dilution technique. The organisms tested varied in pattern of susceptibility but were more sensitive at high concentrations. The zone of inhibition of aqueous extract of Newbouldia laevis on test organisms ranged from 4.0 to 15 mm while the ethanolic extracts of Newbouldia laevis on test organisms ranged from 6.5 to 21.00 mm. The comparative susceptibility of test bacteria to Newbouldia and ciprofloxacin showed that there was a significant difference in the antibacterial activity of leaf extract and the antibiotic standard. The MIC values ranged from 12.5 mg/ml to 25 mg/ml. The extract showed a higher antibacterial activity against E. coli, Bacillus spp and S. epidermidis. The result of the study suggests that the leaf extract of N. laevis has the potential and could be used as a source for new broad spectrum antibiotics to treat ear infections caused by test organisms.

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Section: Introductionmentioning

confidence: 99%

In Vitro Evaluation of Ethanolic and Aqueous Crude Extracts of Newbouldia laevis Leaves on Bacterial Isolates from Ear Infections

Kanu

Kalu

2018

IJPPE

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“…Hence, the subjectively assessed Health related quality of life (QOL) is steadily increasing in clinical medicine. 3 Though there are different QOL index to measure the heath related QOL but Baumann et al 3 developed a novel disease specific QOL questionnaire which assesses the severity of subjective symptoms; as Chronic Otitis Media Outcome Test 15 (COMOT 15). 1,[3][4][5] This test was shown to be valid, reliable and sensitive tool for health related QOL in patients with COM.…”

Section: Introductionmentioning

confidence: 99%

Comparison between pre and post- operative chronic otitis media outcome (COMOT-15) in patients who underwent cartilage myringoplasty in Kathmandu University Hospital: The Nepal scenario

et al. 2017

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Background: The study was conducted to compare the pre and post-operative outcome of quality of life in patients who underwent cartilage myringoplasty with COMOT-15 (Chronic otitis media outcome test-15).Methods: 37 patients were included in the study that underwent endoscopic cartilage myringoplasty. COMOT-15 questionnaire was used pre and 6 months post-operatively to see the quality of life outcome. Along with that audiological testing was also performed. Results: There were total 37 patients (males 19 and females 18) with the mean age of 24.32±/-11.1years, and age range of 18-61years participated in all questionings and examination. The comparison of COMOT-15 Pre and Post-operative questionnaires analysis showed statistically significant improvement in all scales except for mental health. The audiological result also showed clear association of audiometry results with hearing function.Conclusions: The cartilage myringoplasty has beneficial effect in disease specific health related quality of life, as well there is clear association between hearing function scale and audiological evaluation. So, it is useful to perform cartilage myringoplasty wherever necessary.

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“…In addition, further symptoms of CSOM such as persistent discharge from the ear, pain, etc., may result in an impairment of the patient's health. In cases of cholesteatoma, complications like facial nerve paralysis, meningitis, cerebellar abscess, sigmoid sinus thrombosis may develop and potentially threaten the patient's life 6 . This study was conducted to know the number of patients with CSOM getting operated and also to know the clinical profile of patients with CSOM, visiting our tertiary health centre of Nashik City.…”

Section: Introductionmentioning

confidence: 99%

“…CSOM is associated with significant functional limitations of hearing. This frequently results in communication problems impeding social interaction and professional life 6 . In addition, further symptoms of CSOM such as persistent discharge from the ear, pain, etc., may result in an impairment of the patient's health.…”

Section: Introductionmentioning

confidence: 99%

Retrospective Study of Clinical Profile of Patients with Chronic Suppurative Otitis Media at a Tertiary Health Centre

Kulkarni¹,

Burse²,

Patil³

et al. 2014

mvpjms

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Introduction: Chronic Suppurative Otitis Media (CSOM) is frequently associated with symptoms of inflammation like discharge from the ear or pain. In many cases, patients suffer from hearing loss causing communication problems and social withdrawal. Tubotympanic type of chronic suppurative otitis media is characterized by a perforation of pars tensa, while marginal & attic perforations are pathognomonic of attico-antral variety. The latter category is usually associated with the presence of cholesteatoma. In cases of cholesteatoma, complications like facial nerve paralysis, meningitis, cerebellar abscess, sigmoid sinus thrombosis may develop and potentially threaten the patient's life. The aim of this study was to retrospectively perform analysis of patients suffering from Chronic Suppurative Otitis Media, visiting our Tertiary Health Centre, Nashik. Materials and Methods: This was a retrospective study, conducted in a tertiary care medical college hospital over a period of 5 years. The study group comprised 528 patients in and around Nashik District and were subjected to Tympanoplasty or Mastoid surgery. Results: Complete data records from 528 patients were available for statistical analysis. Maximum numbers of patients were in age group 21-40. High prevalence of CSOM was found in females. 408 patients had CSOM of Safe type. 97 patients had CSOM of unsafe type, whereas 23 patients had unsafe CSOM with complications. 381 patients underwent Type 1 Tympanoplasty, while 31 patients underwent Modified Radical Mastoid Surgery. 61 patients were operated for MRM with Tympanoplasty and 28 patients were operated for MRM with Myringostapediopexy. 27 patients were operated for revision tympanoplasty. Different methods of tympanoplasty were performed. Simple underlay was done in 123 patients. Maximum patients about 245 were operated by cartilage support method of tympanoplasty. Anterior tucking was done in 40 patients. Myringostapediopexy was done in 28 patients. Ossiculoplasty with tragal or conchal cartilage was done in 61 patients. Graft was not placed in 31 patients. Temporalis fascia was used in maximum patients. In 90.9% of patients temporalis fascia was used. Fascia Lata was used in 3.2% of patients. Conclusion: Retrospective study of patients with CSOM shows: females were affected more than males. Majority of patients were in age group of 21 to 40 years. The reason could be that this age group is socially active and health conscious. 77.3% of patients had safe CSOM while 22.7% of patients had unsafe CSOM. 2.27% of patients had extra-cranial complication, and 2.08% of patients had intracranial complications. 5.1% of patients underwent revision tympanoplasty surgery. Temporal is fascia as a graft material was used for tympanoplasty in maximum patients, and cartilage support method of tympanoplasty was used in majority of patients. Maximum patients were operated in year 2012. This was due to conduction of camps in peripheral areas around Nashik City which shows that CSOM is more common in patients of lower socio...

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General and disease-specific quality of life in patients with chronic suppurative otitis media - a prospective study

Cited by 88 publications

References 17 publications

<i>In Vitro</i> Evaluation of Ethanolic and Aqueous Crude Extracts of <i>Newbouldia laevis</i> Leaves on Bacterial Isolates from Ear Infections

<i>In Vitro</i> Evaluation of Ethanolic and Aqueous Crude Extracts of <i>Newbouldia laevis</i> Leaves on Bacterial Isolates from Ear Infections

Comparison between pre and post- operative chronic otitis media outcome (COMOT-15) in patients who underwent cartilage myringoplasty in Kathmandu University Hospital: The Nepal scenario

Retrospective Study of Clinical Profile of Patients with Chronic Suppurative Otitis Media at a Tertiary Health Centre

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