General and advanced methods for the detection and measurement of aflatoxins and aflatoxin metabolites: a review

Mahfuz, Mustafa; Gazi, Md. Amran; Hossain, Muttaquina; Islam, Md. Rezaul; Fahim, Shah Mohammad; Ahmed, Tahmeed

doi:10.1080/15569543.2018.1514638

Cited by 23 publications

(14 citation statements)

References 124 publications

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“…ese methods include the LC technique, which is highly sensitive but slower than other methods [52]. On the other hand, ELISA for the analysis of aflatoxins is considered an alternative immunochemical approach to chromatography analysis due to its rapidity, simplicity, and sensitivity.…”

Section: Discussionmentioning

confidence: 99%

The Occurrence of Aflatoxins in Date Palm (Phoenix dactylifera L.) Worldwide

Almaghrabi

2022

Journal of Food Quality

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Due to global warming, the risk of aflatoxins exposure through the consumption of contaminated food has increased. Aflatoxins pose serious health hazards to humans’ and animals’ health because of their carcinogenic, mutagenic, and teratogenic properties and their immunosuppressive effects. Aflatoxin contamination in various agricultural commodities has attracted much attention worldwide. Date palm fruits are among these important commodities that are vulnerable to fungal contamination and consequent aflatoxins production. Furthermore, dates are often consumed directly without any further processing, which may result in direct exposure to aflatoxins. Moreover, dates are the second dried fruits traded worldwide, which reflects the widespread consumption of dates due to their nutritive values in addition to religious and cultural values. Accordingly, this review summarizes and discusses the frequency and incidence of aflatoxin contamination in dates worldwide and outlines the analytical procedure for aflatoxin determination in dates for the first time. The susceptibility of date palm fruits to aflatoxins contamination has been documented at various levels in several regions. The findings urged the importance of conducting more comprehensive studies on aflatoxin occurrence and contamination levels in dates as a likely contributor to the dietary exposure to aflatoxins.

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Section: Discussionmentioning

confidence: 99%

The Occurrence of Aflatoxins in Date Palm (Phoenix dactylifera L.) Worldwide

Almaghrabi

2022

Journal of Food Quality

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“…Further these methods can be categorized into chemical analysis, biological identification, instrumental analysis, and immunoassays (Yan et al, 2020). Moreover, there are factors to be considered when selecting the quantifying method of aflatoxins such as specificity, sensitivity, reliability, and simplicity (Mahfuz et al, 2018). Aflatoxins are controlled in multiple countries and the legal limits range from 0 to 50 ng/g (Kolosova et al, 2006;Mahfuz et al, 2018).…”

Section: Detection Techniques Of Aflatoxin In Edible Plant Oilsmentioning

confidence: 99%

Aflatoxin Occurrence, Contamination, Detection, and Decontamination with Special Emphasis on Coconut Oil: A Review

2023

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Purpose: Coconut oil is one of the commonest and profusely used plant oils in Asian cuisine. Many studies are being carried out aiming at preventing/eliminating potential aflatoxin contamination of the oil or its products along the value chain. The present review analytically provides an overview of aflatoxin occurrence, contamination, detection, and decontamination of vegetable oils with special emphasis on coconut oil.Research Method: Findings and conclusions of studies related to aflatoxins, that are published in authentic sources were reviewed and presented in a chronological manner. Based on the information, current detection and decontamination methods for aflatoxins in edible plant oils were demonstrated.Findings: Complete decontamination of aflatoxins from edible oils seemed impossible, but reducing the accumulated concentrations below the permissible levels seemed possible. The use of chemical agents like alkalis, the most commonly practiced method on a commercial scale, adversely affects human health and the environment. UV irradiation is a promising physical decontamination method of oil with aflatoxins and combining UV irradiation with other potential methods such as the use of adsorbents showed an enhanced efficacy. However, further studies are required to ensure the effective and safe use of biological methods in aflatoxin-contaminated edible oils. Research Limitations:Research gaps in the application of biological decontamination methods in edible oils especially in coconut oil were found.Originality/ Value: This paper critically and aimfully analyzes the relevant information with a view to find gaps thereby showing new directions for applied research to assess nutritional, sensory, and quality attributes in the oils and value-added products, subjected to biological treatments.

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“…The method have capacity of determining the toxins in a single run (Di Mavungu et al, 2009). Before MS, HPLC separates the sample into chemical compunds after that MS ionizes the molecules, afterward sort and identify the molecules according to their mass-to-change ratio (Mahfuz et al, 2018). Njumbe et al (2015) used LC-MS/MS method for the analysis of 23 mycotoxins including AFB 1 in different sorghum varieties.…”

Section: Liquid Chromatography Tandem Mass Spectrometrymentioning

confidence: 99%

Analytical Methods for Determination of Aflatoxin B1 in Animal Feeds and Feedstuffs

Mushtaq

Daş

Aksoy

2020

Erciyes Üniversitesi Veteriner Fakültesi Dergisi

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Aflatoxin B 1 (AFB 1 ) is an Aspergillus spp. produced mycotoxins which is identified as one of the key contaminant of feeds and toxic to some degree to all species tested to date. Because of its hepatocarcinogenic nature, AFB 1 has obtained significant attention in past few years. A number of analytical, diagnostic and immunological procedures are available for assessment and estimation of AFB 1 in different feeds such as enzyme linked immunosorbent assay (ELISA), thin layer chromatography (TLC), high performance liquid chromatography (HPLC), liquid chromatography tandem mass spectrometry (LC-MS/MS) and electrochemical immunosensors (ECI). All available analytical methods for determination of AFB 1 principally included the same steps like, sampling, sample preparation, detection, confirmation, and finally risk assessment. HPLC approaches are most commonly used nowadays because of their high accuracy, precision and sensitivity. Since late 20 th century, many countries including Turkey has imposed strict rules and regulations regarding AFB 1 in food and animal feed related industry to protect the consumer from the detrimental effects of the toxin. In this article, a number of analytical techniques for determination of AFB 1 in feeds and feedstuffs starting from sampling to risk assessment and international regulations are reviewed.

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General and advanced methods for the detection and measurement of aflatoxins and aflatoxin metabolites: a review

Cited by 23 publications

References 124 publications

The Occurrence of Aflatoxins in Date Palm (Phoenix dactylifera L.) Worldwide

The Occurrence of Aflatoxins in Date Palm (Phoenix dactylifera L.) Worldwide

Aflatoxin Occurrence, Contamination, Detection, and Decontamination with Special Emphasis on Coconut Oil: A Review

Analytical Methods for Determination of Aflatoxin B1 in Animal Feeds and Feedstuffs

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