“…This process involves many genes encoding growth factors, including epidermal growth factor, VEGF, keratinocyte growth factor, hepatocyte growth factor, platelet-derived growth factor, basic fibroblast growth factor, and angiopoietins. It has been reported that genes encoding these growth factors have an ulcer healing effect in vivo [2,[32][33][34]. Moreover, gene therapy has been tried for gastric cancer in vitro and in vivo with various therapeutic genes, namely p53 [35], FHIT [36], NK4 [37,38] and the Fas ligand [39].…”