Abstract:Small non-coding RNAs (sRNAs) in bacteria are important regulatory molecules for controlling virulence. In Vibrio spp., Qrr sRNAs are critical for quorum-sensing pathways and regulating the release of some virulence factors. However, the detailed role of Qrr sRNAs in the virulence of Vibrio parahaemolyticus remains poorly understood. In this study, we identified a Vibrio sRNA Qrr5 that positively regulates cytotoxicity and adherence in Caco-2 cells by primarily regulating the T3SS1 gene cluster. A number of 18… Show more
“…Regulatory molecules, such as small non-coding RNAs can also control virulence since they are critical for quorum-sensing pathways and the regulation of some virulence factors. As such, a comprehensive transcriptome profile of Vibrio parahaemolyticus during infection in Caco-2 cells, has been released [ 10 ].…”
Foodborne microorganisms substantially impact food safety and contribute considerably to the public health and economic burden of infectious diseases worldwide [...]
“…Regulatory molecules, such as small non-coding RNAs can also control virulence since they are critical for quorum-sensing pathways and the regulation of some virulence factors. As such, a comprehensive transcriptome profile of Vibrio parahaemolyticus during infection in Caco-2 cells, has been released [ 10 ].…”
Foodborne microorganisms substantially impact food safety and contribute considerably to the public health and economic burden of infectious diseases worldwide [...]
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